Related analgesics

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  • I n its broadest sense the alleviation of pain is one of the most important goals of scientists. Among natural products there is nolie whirh performs this function as surely and as dramatically as does morphine. Unfortunately morphine elicits other reactions, many of them undesirable ones, and it is therefore little wonder that it has been subjected to an investigational scrutiny unequalled in science.

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  • Antidepressant Medications The tricyclic antidepressants [amitriptyline, imipramine, nortriptyline, desipramine (TCAs; Table 12-1)] are extremely useful for the management of patients with chronic pain. Although developed for the treatment of depression, the tricyclics have a spectrum of dose-related biologic activities that include the production of analgesia in a variety of clinical conditions. Although the mechanism is unknown, the analgesic effect of TCAs has a more rapid onset and occurs at a lower dose than is typically required for the treatment of depression.

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  • A double-freeze technique was used with two 3–minute periods of freezing separated by a 5–minute period to allow thawing of the frozen cervical tissue. Nitrous oxide (N2O) gas was used to achieve the freeze. Consistent with current MOH policy related to invasive gynecologic procedures such as intrauterine contraceptive device insertion, prophylactic antibiotics were provided at the time of the treatment. Those who complained of cramping, lower abdominal pain during or immediately after cryotherapy were given a prescription for several doses of an analgesic such as ibuprofen.

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  • Reduce hiv risk and vulnerability in settings of humanitarian concern. Contingency plans for essential HIV services should be part of national HIV plans in order to ensure continuity of HIV treatment and care in settings of humanitarian concern, including buffer stocks of essential medicines and commodities (including antiretroviral medicines, condoms, diagnostic assays, opioid analgesics and sterile injecting supplies).

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