Cervical cancer is the second most prevalent cancer among women worldwide, and infection with Human Papilloma Virus (HPV) has been identified as the causal agent for this condition. The natural history of cervical cancer is characterized by slow disease progression, rendering the condition in essence preventable and even treatable when diagnosed in early stages.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:The pathophysiological function of peroxisome proliferator-activated receptor-γ in lung-related diseases...
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Suspected idiopathic sclerosing orbital inflammation presenting as immunoglobulin G4-related disease: a case report
Background: Dercum’s disease (DD) is characterised by obesity and chronic pain ( 3 months) in the adipose tissue. The pathogenesis of DD is unknown, but inflammatory components have been proposed. In previous reports and studies, an inconsistent picture of the histological appearance of the adipose tissue in DD has been described. The aim of this investigation was to examine the histological appearance of adipose tissue in patients with DD, with particular focus on inflammatory signs. Methods: Fat biopsies were sampled from painful regions from 53 patients with DD.
(BQ) Part 1 book "Bone and joint imaging" presents the following contents: Basic science, diagnostic techniques, imaging and interventional procedures of the spine, imaging of the postoperative spine, rheumatoid arthritis and related diseases, connective tissue disease, degenerative diseases,...
This working paper focuses on the relevance of social, socioeconomic and behavioural
factors on health status and mortality in a longitudinal setting and in a life-course perspective.
First, we identify those factors which determine the health status of people aged 60+ in
Germany. Based on this, our second aim is to find factors which determine transitions from
good general health status, or from the absence of specific diseases, to a bad general health
status or the presence of specific diseases.
As for the fi rst edition of this volume, the chapters comprise comprehensive discussions of
the some of the major non-infectious disorders of fi nfi sh. It is the second volume of a threevolume
series on fi sh diseases and disorders; Volume 1 deals with parasitic diseases and
Volume 3 with microbial diseases. Reviews in the three volumes are written by leading
international authorities who are actively working in the area or who have contributed
greatly to our understanding of specifi c diseases or disorders....
In writing An Atlas of Parkinson’s Disease and
Related Disorders, I have been conscious of the
need to find an appropriate match between the
text and the illustrative material. The text is
designed to provide a basic overview of the conditions
discussed, inevitably concentrating on those
areas which lend themselves best to photographic
illustration. Some movement disorders, by their
very nature, do not lend themselves to still
photography whereas others, characterized by
sustained postures, are ideally suited to the technique.
Association rules represent a promising technique to find
hidden patterns in a medical data set. The main issue about
mining association rules in a medical data set is the large
number of rules that are discovered, most of which are irrelevant.
Such number of rules makes search slow and interpretation
by the domain expert difficult. In this work, search
constraints are introduced to find only medically significant
association rules and make search more efficient.
Polyostotic fibrous dysplasia.
See also "Papulonodular Skin Lesions."
A proliferation of melanocytes results in the following pigmented lesions: lentigo, melanocytic nevus, and melanoma (Chap. 83). In an adult, the majority of lentigines are related to sun exposure, which explains their distribution.
Pure Red Cell Aplasia: Treatment History, physical examination, and routine laboratory studies may disclose an underlying disease or a suspect drug exposure. Thymoma should be sought by radiographic procedures. Tumor excision is indicated, but anemia does not necessarily improve with surgery. The diagnosis of parvovirus infection requires detection of viral DNA sequences in the blood (IgG and IgM antibodies are commonly absent). The presence of erythroid colonies has been considered predictive of response to immunosuppressive therapy in idiopathic PRCA.
Epidemiology Idiopathic MDS is a disease of the elderly; the mean age at onset is 68 years. There is a slight male preponderance. MDS is a relatively common form of bone marrow failure, with reported incidence rates of 35 to 100 per million persons in the general population and 120 to 500 per million in the elderly. MDS is rare in children, but monocytic leukemia can be seen.
Therapy-related MDS is not age-related and may occur in as many as 15% of patients within a decade following intensive combined modality treatment for cancer. Rates of MDS have increased over time,...
The English poet, John Keats, explored this relationship when he asked: “Do we retreat from
the reality of the outer world into ourselves at times, or do we retreat from the pressures of
the outside world into the reality of our inner selves?” (Philipp, 2001a). In taking this
question further, the doctor-poet, Dannie Abse, musing on it in 1993, noted that:
“imaginative daydreaming is an escape from the precipitous pessimism of living or dealing
with problems and the sphere of sorrows, and it is used to restore balance” (op.cit.).
On the initiative of the International Dental Federation, a meeting of consultants
was convened by the World Health Organization in 1964 to consider the
classification of diseases of the buccal cavity in relation to the impending Eighth
(1965) Revision of the International Classification of Diseases (ICD). It was
recognized that a manual and guide should be compiled to assist in the
application of the ICD to dentistry and stomatology. Accordingly, a text was
drafted and tested in four countries, then revised and published for general use.
Senescence is a biological process that causes a progressive deterioration of structure and function of all organs chronologically. Recent studies have revealed the detailed molecular mechanisms of senescence using cell culture system and experimental organisms. It is thought that senescence is a potential cause for the development of various age-related disorders such as cancer, cardiovascular and neurodegenerative disorders.
Pathophysiology Bone marrow failure results from severe damage to the hematopoietic cell compartment. In aplastic anemia, replacement of the bone marrow by fat is apparent in the morphology of the biopsy specimen (Fig. 102-1) and MRI of the spine. Cells bearing the CD34 antigen, a marker of early hematopoietic cells, are greatly diminished, and in functional studies, committed and primitive progenitor cells are virtually absent; in vitro assays have suggested that the stem cell pool is reduced to ≤1% of normal in severe disease at the time of presentation.
Persistent Parvovirus B19 Infection Chronic parvovirus infection is an important, treatable cause of PRCA. This common virus causes a benign exanthem of childhood (fifth disease) and a polyarthralgia/arthritis syndrome in adults. In patients with underlying hemolysis (or any condition that increases demand for red blood cell production), parvovirus infection can cause a transient aplastic crisis and an abrupt but temporary worsening of the anemia due to failed erythropoiesis.
Harrison's Internal Medicine Chapter 131. Diphtheria and Other Infections Caused by Corynebacteria and Related Species
Corynebacterium diphtheriae. Toxigenic strains of C. diphtheriae produce a protein toxin that causes systemic toxicity, myocarditis, and polyneuropathy. The toxin is associated with the formation of pseudomembranes in the pharynx during respiratory diphtheria. While toxigenic strains most frequently cause pharyngeal diphtheria, nontoxigenic strains commonly cause cutaneous disease.
Respiratory Diphtheria The clinical diagnosis of diphtheria is based on the constellation of sore throat; adherent tonsillar, pharyngeal, or nasal pseudomembranous lesions; and low-grade fever. In addition, diagnosis requires the isolation of C. diphtheriae or the histopathologic isolation of compatible gram-positive organisms.