For over 50 years, interest has been expressed in optimizing drug therapy through
delivery system design. For many years this revolved around incorporating drugs
into erodible or inert polymers, which then acted as platforms for controlled release,
an approach that has been well reviewed in the literature.
The most established nationwide medical registry in Germany is the Perinatal Registry, which collects
maternal health records concerning pregnancy, delivery and perinatal outcome from now more than
1100 hospitals. Over the past 16 years, data collection was transformed from printed questionnaires to
digital records. A special web-based information source of the German Perinatal Registry does not
The field of Pain Medicine has evolved over the last 20 years to include an
increasing array of sophisticated and technologically complex diagnostic and therapeutic
procedures. Concurrent to this advancement has been the development of a
battery of pharmacological options to treat pain, from extended-release formulations
of analgesics to antidepressants and anticonvulsants designed to treat specific types of
Akcros stabilizer/activators have been formulated to provide
controlled, uniform gas evolution for the production of PVC foams
utilizing azodicarbonamide as the blowing agent. The ABC series of
blowing agent catalysts are primary materials and act as both heat
stabilizers and gas generation activators. No secondary stabilizer is
normally required. Thus, with the availability of such blowing agent
catalysts, the use range of azodicarbonamide is extended to a
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Intestine-Specific, Oral Delivery of Captopril/ Montmorillonite: Formulation and Release Kinetics
Information about the topology and link-level characteristics
of a network is critical for many applications including
network diagnostics and management. However, this information
is not always directly accessible; subnetworks may not cooperate
in releasing information and widespread local measurement
can be prohibitively expensive. Network tomographic techniques
obviate the need for network cooperation, but the majority
assume probing from a single source, which imposes scalability
limitations because sampling traffic is concentrated on network
links close to the source.
Herbicides are much more than just weed killers. They may exhibit beneficial or adverse effects on other organisms. Given their toxicological, environmental but also agricultural relevance, herbicides are an interesting field of activity not only for scientists working in the field of agriculture. It seems that the investigation of herbicide-induced effects on weeds, crop plants, ecosystems, microorganisms, and higher organism requires a multidisciplinary approach. Some important aspects regarding the multisided impacts of herbicides on the living world are highlighted in this book.
An additional RCT was identified and included which compared metformin immediate-release
(MIR) with metformin extended-release (MXR).65 The GDG subsequently felt that there might
be relevant and important information in existence on the AE profile of these two formulations
which had not been found during our search. Thus a focused call for evidence to all stakeholders
was made. Following this, the GDG considered two RCTs (published in the same paper) which
compared MXR against placebo,66 and to a retrospective chart review comparing immediaterelease
and extended-release formulations.
Overall, the evidence appraised suggested that monotherapy with metformin produced
significantly greater improvements in glycaemic control (i.e. HbA1c and FPG/fasting blood
glucose (FBG)) when it was compared with placebo, diet and sulfonylureas. Head-to-head
comparisons with other antidiabetic agents (i.e. alpha-glucosidase inhibitors, thiazolidinediones,
meglitinides and insulin) and extended-release formulations of metformin, failed to show more
benefit for glycaemic control than standard monotherapy with metformin.
The RBI formulates implements and monitors the monetary policy. It is responsible for regulating
non-banking financial services companies, which operate like banks but are otherwise not
permitted to carry on the business of banking.