Forensic Engineering Investigation is a compendium of the investigative methodologies used by engineers and scientific investigators to evaluate some of the more common types of failures and catastrophic events. In essence, the book provides analyses and methods for determining how an entity was damaged and when that damage may have legal consequences. The material covers 21 common types of failures, catastrophic events, and losses that forensic engineers routinely assess.
Computational Science and Engineering (CS&E) is widely accepted, along with theory and experiment, as a crucial third mode of scientific investigation and engineering design. This series publishes research monographs, advanced undergraduate- and graduate-level textbooks, and other volumes of interest to a wide segment of the community of computational scientists and engineers. The series also includes volumes addressed to users of CS&E methods by targeting specific groups of professionals whose work relies extensively on computational science and...
This report provides baseline information on investigations undertaken as part of the Collaboration for
Agriculture and Rural Development CARD Project 050/04VIE “Improvement of export and domestic markets
for Vietnamese fruit through improved post-harvest and supply chain management”. This collaborative
project is funded by AusAID and administered by Hassall and Associates International.
The aim of the study was to reconstruct sedimentary environments of the MR1 core and investigate geotechnical properties of sedimentary facies through the piezocone penetration test (CPTU). A core at the Vinhlong province, Mekong River Delta (MRD), sufficiently presented the Holocene facies of the area. Eight facies were identified based upon sedimentary properties. Characteristics of the units showed
Basic blue 41 is a very stable dye using in wool weaving industry. Fenton reaction is
often used to decompose stable substances in wastewater. In this study planed experiments method
was used to investigate the effect of three factors, that are pH, H2O2 and Fe2+ concentration on
COD reduction. The response surface was determined by program Modde 5.0, the optimal reaction
conditions was: Fe2+ concentration is 120 mg/L, H2O2 concentration is 10 mM, pH is 4.
In this paper we propose a methodology for investigating the relationship between architectures of natural language generation (NLG) systems and stylistic properties of texts. Biber's (1988) methodology is used to obtain both the characterisation of style of our corpus and the division of the corpus into sets of linguistically similar texts. These sets will be used for studying the architectural aspects.
An embedded fiber Bragg grating (FBG) sensor, which fabricated in IMS, for temperature sensing was proposed. The temperature responses of the in-fiber Bragg gratings (FBGs) have been investigated. It was found that these responses ranged from 10.6 pm/°C to 12.0 pm/°C. The temperature sensitivity of the FBGs was 0.2°C. The strain responses remained temperature independent over a temperature range of 20 – 180 ◦C.
We used generalized two-dimensional NMR–NMR correlation to examine
the effect of potassium ions on the conformation transition in silk fibroin
to investigate the possibility that the fairly high K
ion content found in
the distal end of silk-secreting ducts in the silkworms could have a bearing
on natural formation of the silk fiber.
The catalytic reaction mechanism and binding of substrates was investi-gated for the multisubstrateDrosophila melanogasterdeoxyribonucleoside
kinase. Mutation of E52 to D, Q and H plus mutations of R105 to K and
H were performed to investigate the proposed catalytic reaction mech-anism, in which E52 acts as an initiating base and R105 is thought to sta-bilize the transition state of the reaction.
Prolonged exposure of pancreatic beta cells to the sulfonylureas glibenca-mide and tolbutamide induces subsequent desensitization to the actions of
these drugs. The precise mechanisms underlying this desensitization remain
unknown, prompting the present study, which investigated the impact of
prolonged sulfonylurea exposure on glucose and energy metabolism using
clonal pancreatic BRIN-BD11 beta cells.
The coat proteins of filamentous phage are first synthesized as transmem-brane proteins and then assembled onto the extruding viral particles. We
investigated the transmembrane conformation of the Pseudomonas aerugi-nosa Pf3 phage coat protein using proton-decoupled
solid-state NMR spectroscopy.
The conduction of protons through human Nox2 has pre-viously been shown to be dependent upon His115. Align-ment of sequences for both animal and plant Nox proteins
indicated that histidines 115 and 119 are both highly con-served, while His111 was conserved among animal homo-logues of Nox1–4. To investigate the possible role that these
histidine residues might play in the conduction of protons
through Nox2, we have introduced both paired and single
mutations into these histidine residues.
Taking this route sets up a dual goal: (a) from the generic paraphrasing perspective - an objective evaluation of paraphrase acquisition performance on a concrete application dataset, as well as identifying the additional mechanisms needed to match paraphrases in texts; (b) from the RE perspective investigating the feasibility and performance of a generic paraphrase-based approach for RE. Our conﬁguration assumes a set of entailing templates (non-symmetric “paraphrases”) for the target relation.
Learning objectives of this chapter include: Define and distinguish forensic science and criminalistics, Understand the importance of an investigator's understanding of crime laboratory capabilities, Describe the three measures of effectiveness of crime laboratories, Distinguish the Frye test from the Daubert test regarding the admissibility of scientific evidence, Explain the role and importance of DNA analysis in criminal investigation,…
This topic will describe arson and explosives investigations. In this chapter you will learn: Discuss the steps in the preliminary investigation of arson, be familiar with various types of burn indicators, describe ignition devices that may be used in arson, assess several common motivations of arsonists for setting fires, explain the scientific methods used in arson investigation, list several groups of people whom an arson investigator should interview,...
A ubiquitin ligase (E3) functions at the crossroad between ubiquitin acti-vation and the attachment of ubiquitin to protein substrates. During this
process, the E3 interacts with both a substrate and a ubiquitin-conjugat-ing enzyme (E2). Although a major goal when investigating an E3 is to
identify its substrates, recent evidence indicates that the E2 dictates the
type of ubiquitin modification that will occur on the substrate.
The specificity of the aglycone-binding site ofEscherichia colia-xylosidase
(YicI), which belongs to glycoside hydrolase family 31, was characterized
by examining the enzyme’s transxylosylation-catalyzing property. Acceptor
specificity and regioselectivity were investigated using various sugars as
acceptor substrates anda-xylosyl fluoride as the donor substrate.
NAD(P)H regeneration is important for biocatalytic reactions that require
these costly cofactors. A mutant phosphite dehydrogenase (PTDH-E175A⁄A176R) that utilizes both NAD and NADP efficiently is a very
promising system for NAD(P)H regeneration. In this work, both the kin-etic mechanism and practical application of PTDH-E175A⁄A176R were
investigated for better understanding of the enzyme and to provide a basis
for future optimization.
We report experiments to investigate the role of the physio-logically relevant protein tyrosine kinase Lck in the ordered
phosphorylation of the T-cell receptorfchain. Six synthetic
peptides were designed based on the sequences of the
immunoreceptor tyrosine-based activation motifs (ITAMs)
of thefchain. Preliminary
H-NMRstudies of recombinant
f chain suggested that it is essentially unstructured and
therefore that peptide mimics would serve as useful models
for investigating individual ITAM tyrosines....
This paper investigates two elements of Maximum Entropy tagging: the use of a correction feature in the Generalised Iterative Scaling (Gis) estimation algorithm, and techniques for model smoothing. We show analytically and empirically that the correction feature, assumed to be required for the correctness of GIS, is unnecessary. We also explore the use of a Gaussian prior and a simple cutoff for smoothing. The experiments are performed with two tagsets: the standard Penn Treebank POS tagset and the larger set of lexical types from Combinatory Categorial Grammar. ...