Xem 1-20 trên 33 kết quả Significant discoveries
  • Nevertheless, vitalism continued to find its way into the description of life processes. For instance, Pasteur writing about his discovery of the importance of oxygen availability for sugar fermentation by yeast, to be later known as the Pasteur effect, argued for the exclusive dependency of intact cell structure, a variant of cell theory postulated by Matthias Schleiden, Theodor Schwann, and their predecessors, and “ferments”, a set of biocatalysts represented as vital forces.

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  • In the past years, research in the field of responsive business environments has had many successes. The most significant of these has been the development of powerful new tools and methodologies that advance the subject of Business Intelligence (BI). This book provides the BI practitioner and researcher with a comprehensive view of the current art and the possibilities of the subject.

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  • It has been an honor and a privilege to chair the committee on the state of science in nuclear medicine. As a diagnostic radiologist, a clinicianscientist, and the chairperson of a large academic radiology department, I have been exposed to the many advances in nuclear medicine and have observed their clinical benefits up close. Participating in this review, however, has allowed me to step back and appreciate the magnitude of the progress that has been achieved, and the crucial role that government funding has played in it.

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  • THE PETROLEUM AND NATURAL GAS CONSERVATION BOARD Was created in 1938. Its responsibilities have since been expanded to all types of energy resources, and it is now known as the Energy Resources Conservation Board (ERCB). The occasion of the organization's fiftieth anniversary caused many of us to think about the significant role that the Board has played in the development of the province's energy industry.

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  • With regard to the destination of the invested funds in terms of sector allocation, we are restricted to use data obtained about business angel networks (see EBAN, 2010c). While it is generally difficult to apply insights gained from networks to the overall BA market, it might be fair to assume such sector data to be representative for the market in general.

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  • This plan sets out our high level business priorities and delivery plans for 2012-2013, not only to provide core services to offenders in prison and on probation in England and Wales, but also to continue to improve the way we work, to achieve better outcomes for the public at less cost to the taxpayer. The reforms and activities in this plan are part of the wider Ministry of Justice Transforming Justice programme, to deliver a justice system which is more effective, less costly, and more responsive to the public.

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Discovery of significant variants containing large deletions in the 5'UTR of human hepatitis C virus (HCV)

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  • Ending the Affair examines the state of short form1 television current affairs in Australia today, questioning its future while drawing lessons from the past. The research project from which this book emerged was a history of television current affairs formats in Australia. Funded by the Australian Research Council, its original motivation was to understand the significance of the changes that had occurred in these television formats and their function, particularly since the network upheavals of the late 1980s....

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  • This proposition can be illustrated with an analysis of discrimination in South Africa, where blacks are four to five times as numerous as whites. Discrimination against blacks has also significantly hurt whites, although some white groups have benefitted (see Becker [1971, pages 30 - 31], and Hutt [1964]). Its sizable cost to whites suggests why apartheid and other blatant forms of Afrikaaner discrimination eventually broke down.

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  • This book does not provide a comprehensive overview of Multiple Myeloma but a collection of chapters with in-depth information of distinct hot topics in the diagnostic, research and therapeutic fields. The dynamics of testing new drugs for multiple myeloma treatment in clinical trials is breathtaking. Scientific discoveries have uncovered complicated pathogenesis of multiple myeloma; complicated reactions to treatment lead to the creation of super cocktails. Curability of multiple myeloma is a question that is being discussed by the entire professional myeloma world.

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  • Over the years since the adoption and subsequent ratification of the Convention on the Rights of the Child by 193 countries, significant efforts and great strides have been made to ensure that children (defined as people under the age of 18), regardless of gender, origin, religion or disability status, need special care and protection because they are often the most vulnerable. Accordingly, today, more than ever before, young people are recognized as rights-bearing citizens and are playing an active role in asserting their rights.

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  • The next important milestone emerged in 1990 when three independent working groups described the role of2-glycoprotein I as a target antigen in antiphospholipid antibodies’ action (Galli M, et al; 1990, Matsura E, et al; 1990, McNeil HP, et al; 1990). This discovery substantially changed point of view of many of the researchers and also clinical practisers in the topic and it led to research of 2-glycoprotein I structure, function and confirmation of significance of its antibodies presence during the next years....

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  • The significant research in adsorption in the 70s through the 90s could be attributed to the discovery of many new porous materials, such as carbon molecular sieve, and the invention of many new clever processes, notably Pressure Swing Adsorption (PSA) processes. This evolution in adsorption research is reflected in many books on adsorption, such as the ones by Ruthven (1984), Yang (1987, 1997), Jaroniec and Madey (1988), Suzuki (1990), Karger and Ruthven (1992) and Rudzinski and Everett (1992).

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  • To quantify the impact of luck on mutual fund performance, we use the False Discovery Rate (F DR) introduced by Benjamini and Hochberg (1995) in the statistical literature. The F DR measures the proportion of lucky funds among the funds with significant estimated alphas. We extend this methodology by developing a new approach which allows us to separately compute the F DR among funds with significant positive estimated alphas (called hereafter the best funds) and funds with significant negative estimated alphas (called hereafter the worst funds)....

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  • Therapeutic immunosuppression has very broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (e.g., rheumatoid arthritis), skin diseases, allergies and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential.

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  • Editors of compilations such as this tend to stress in their prefaces that significant conceptual advances have been made recently, that novel technical developments have opened extraordinary opportunities for unprecedented discoveries and that the time seemed ripe to take stock and to point out developments which will advance the field in the near future. Well, all of this is true for this book too. It is also true that on such occasions we realize how much we have learned and yet how little we know.

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  • Laetoli in northern Tanzania is one of the most important paleontological and paleoanthropological sites in Africa. It is renowned for the recovery of early hominin fossils belonging to A. afarensis and for the discovery of remarkably well-preserved trails of footprints of hominins. Given the significance of Laetoli for understanding and interpreting the evolutionary history of early hominins the author initiated long-term geological and paleontological investigations at Laetoli and at other fossil localities on the Eyasi Plateau.

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  • This paper addresses all these issues by measuring the impact of luck on mutual fund performance. Specifically, we use the False Discovery Rate (F DR) introduced by Benjamini and Hochberg (1995) in the statistical literature—the F DR measures the proportion of lucky funds among the significant funds. We extend this methodology by developing a new approach which allows us to separately compute the F DR among funds with significant positive estimated alphas (called hereafter the best funds) and funds with significant negative estimated alphas (called hereafter the worst funds).

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  • The discovery of the hormone insulin by Frederick Banting and colleagues in the early 1920’s is one of the greatest medical breakthroughs and has saved millions of lives over the years. The significance of the discovery is underscored by the fact that type 1 diabetics still have an absolute requirement for daily injections of insulin to live. Clearly, today’s insulin treatments have attained levels of sophistication that have greatly improved clinical out‐ come ...

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  • The discovery of high temperature superconductors (HTS) in 1986 by two IBM scientists led to an unprecedented explosion of research and development efforts world-wide because of the significant potential for practical applications offered by these materials. However, the early euphoria created by the exciting prospects was dampened by the daunting task of fabricating these materials into useful forms with acceptable superconducting properties. Progress towards this goal has been hindered by many intrinsic materials problems, such as weak-links, flux-creep, and poor mechanical properties.

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