Xem 1-11 trên 11 kết quả Silico modeling
  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy...

    pdf14p toshiba15 24-10-2011 18 2   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Research In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques associated with Alzheimer's disease...

    pdf26p toshiba17 28-10-2011 24 1   Download

  • Scientific perception of nature relies on a process of transforming data to information, and then information into understanding. Data consist of observations and measurements and information is data organized according to some ontology, i.e. some set of assumptions about what entities exist and how they should be classified. Understanding is a model in the investigator’s mind that describes how the entities relate to each other, a model created in the investigator’s mind as a result of thinking.

    pdf509p phoebe75 01-02-2013 16 3   Download

  • NFκB plays an important role in the immune system in all organisms. In this study, physicochemical properties and modelling of finfish NFκBIα protein was analysed using in silico approach. Finfish species: guppy (Poecilia reticulate), Bicolor damselfish (Stegastes partitus), Channel catfish (Ictalurus punctatus), Coelacanth (Latimeria chalumnae), and Australian ghostshark (Callorhinchus milii) were used in this study.

    pdf10p nganga_06 29-09-2015 6 2   Download

  • The discovery of efficacious new human therapeutic agents is one of humanity’s most vital tasks. It is an enormously demanding activity that requires creativity, a vast range of scientific knowledge, and great persistence. It is also an exceedingly expensive activity. In an ideal world, no education would be complete without some exposure to the ways in which new medicines are discovered and developed. For those young people interested in science or medicine, such knowledge is arguably mandatory....

    pdf293p huutoan1990bk 12-09-2011 85 40   Download

  • During the past two decades, reductionist biological science has generated new empirical data on the molecular foundations of biological structure and function at an accelerating rate. The list of organisms whose complete genomes have been sequenced is growing by the week. Annotations of these sequences are becoming more comprehensive, and databases of protein structure are growing at impressive, indeed formerly unimaginable rates.

    pdf261p beobobeo 01-08-2012 44 9   Download

  • Natural products are a constant source of potentially active compounds for the treatment of various disorders. The Middle East and tropical regions are believed to have the richest supplies of natural products in the world. Plant derived secondary metabolites have been used by humans to treat acute infections, health disorders and chronic illness for tens of thousands of years. Only during the last 100 years have natural products been largely replaced by synthetic drugs.

    pdf524p phoebe75 19-02-2013 22 8   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: " In silico experimentation with a model of hepatic mitochondrial folate metabolism

    pdf11p toshiba17 28-10-2011 18 1   Download

  • MicroRNAs (miRNAs) are small noncoding RNAs (~22 nucleotides) that regulate gene expression by cleaving mRNAs or inhibiting translation. The baboon is a well-characterized cardiovascular disease model; however, no baboon miRNAs have been identified. Evidence indicates that the baboon and human genomes are highly conserved; based on this conservation, we hypothesized that comparative genomic methods could be used to identify baboon miRNAs.

    pdf8p toshiba23 18-11-2011 23 3   Download

  • Mutagenesis is a powerful method directed towards mutating genes or engineering genome for functional analysis, producing mouse models of human disease, and understanding molecular mechanism of biodiversity at different levels of biological organizations. Several insights have been revealed through studies using experimental models, or in silico, on natural mutations in general and site-specific mutagenesis in particular. However, unified text on recent trends in mutagenesis is poorly available within a single cover.

    pdf255p maket1311 16-10-2012 18 2   Download

  • To address questions of protein stability, researchers have increasingly turned to combinatorial approaches that permit the rapid analysis of libraries of protein variants. Phage-displayhasprovedtobeapowerful tool foranalyzingprotein stabilitydue to the large library sizeand the robustnessof the phageparticle toavarietyofdenaturingconditions.

    pdf7p dell39 03-04-2013 9 2   Download

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