The past three decades have witnessed significant advances in the field
of assisted human conception. Following the remarkable perseverance and
triumph of Robert Edwards, Patrick Steptoe, and Jean Purdy, numerous
scientists and physicians from around the world have worked to develop
more effective and safer procedures to treat infertile couples.
Since its first description by Steptoe and Edward, IVF gained popularity among both
doctors and patients. There is many studies on assisted reproduction and they cover
most of the related technical, laboratory as well as clinical aspects. To write a book on
assisted reproduction nowadays seems very difficult due to a wide plethora of related
papers and well-illustrated books. This small-sized book aims at refinement of some
already known points of practical importance in infertility management particularly
Micromanipulation involves a well-integrated set of technologies in assisted reproductive technology (ART). Its applications are diagnostic as well as therapeutic, and it is practiced in mature gametes and all stages of preimplantation embryos.
Fertility drugs can be oral or injectible. The most common fertility drug used is clomiphene
citrate (brand name Clomid or Serophene), which is taken orally to help women who are not
ovulating or who ovulate irregularly to produce one or more mature eggs. Injectibles are called
gonadotropins and stimulate the ovary to produce more follicles in one cycle. Clomiphene citrate
and gonadotropins can be used on their own with intercourse, or combined with AI or IVF.
Success rates depend on many factors, especially maternal age and the quality of the