Stimulated formation

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  • Benzo[a]pyrene (B[a]P) is a common food pollutant that causes DNA adduct formation and is carcinogenic. The report of a positive correlation between human plasma B[a]P levels and body mass index, together with B[a]P’s lipophilicity, led us to test for possible adverse effects of B[a]P on adipose tissue.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines...

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  • Lipid accumulation alters macrophage biology and contributes to lipid retention within the vessel wall. In this study, we investigated the role of adipophilin on triglyceride accumulation and lipid-droplet formation in THP-1-derived macrophages (THP-1 macrophages). In the presence of acetylated low-density lipoprotein, macrophages infected with an adeno-virus expressing human adipophilin showed a 31% increase in triglyceride content and a greater number of lipid droplets compared with control cells....

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  • QDs play an important role mainly in the imaging and as highly fluorescent probes for biological sensing that have better sensitivity, longer stability, good biocompatibility, and minimum invasiveness. The fluorescent properties of QDs arise from the fact, that their excitation states/band gaps are spatially confined, which results in physical and optical properties intermediate between compounds and single molecules. Depending on chemical composition and the size of the core which determines the quantum confinement, the emission peak can vary from UV to NIR wavelengths (400–1350 nm).

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  • During thrombus formation, thrombin, which is abundantly present at sites of vascular injury, activates platelets in part via autocrine-produced ADP. We investigated the signaling pathways by which thrombin and ADP in synergy induced platelet Ca 2+ elevation and procoagulant activity, and we monitored the consequences for the coagulation process.

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  • Selenium is a trace element found in freshwater and the marine environ-ment. We show that it plays a major role in spicule formation in the demo-sponge Suberites domuncula. If added to primmorphs, an in vitro sponge cell culture system, it stimulates the formation of siliceous spicules. Using differential display of transcripts, we demonstrate that, after a 72-h expo-sure of primmorphs to selenium, two genes are up-regulated; one codes for selenoprotein M and the other for a novel spicule-associated protein....

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  • Crk belongs to a family of adapter proteins whose structure allows interaction with tyrosine-phosphorylated proteins and is therefore an important modulator of downstream signals, representing a convergence of the actions of numerous stimuli. Recently, it was demonstrated that chole-cystokinin (CCK) induced tyrosine phosphorylation of proteins related to fiber stress formation in rat pancreatic acini.

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  • The results of the present study show that human platelets take up L-arginine by two transport systems which are compatible with the systems y + and y + L. These Na + -independent transporters have been distinguished by treat-ing platelets with N-ethylmaleimide that blocks selectively systemy + .Systemy + , that accounts for 30–40%of the total transport, is characterized by low affinity forL-arginine, is unaffected byL-leucine, is sensitive to changes of membrane potential and totrans-stimulation. ...

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  • This book was written by people who like to teach for people who like to learn. Its format of questions and short answers lends itself to the dissemination of information as the kinds of “pearls” that teachers are always trying to provide and for which students yearn. The format also permits a lack of formality not available in a standard text. Consequently, the reader will note smatterings of humor throughout the book. Our goal has been to provide a work that readers will enjoy and find useful and stimulating. ...

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  • The units followatried-and-tested 'presentation-explanation-practice' format- They begin with a text (e.g. a rhyme, a dialogue, a story) which has been carefully designed to stimulate interest while at the same time showing the lesson's grammatical focus in context.

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  • Horizontal Gaze Descending cortical inputs mediating horizontal gaze ultimately converge at the level of the pons. Neurons in the paramedian pontine reticular formation are responsible for controlling conjugate gaze toward the same side. They project directly to the ipsilateral abducens nucleus. A lesion of either the paramedian pontine reticular formation or the abducens nucleus causes an ipsilateral conjugate gaze palsy.

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  • THE CYTOKININS WERE DISCOVERED in the search for factors that stimulate plant cells to divide (i.e., undergo cytokinesis). Since their discovery, cytokinins have been shown to have effects on many other physiological and developmental processes, including leaf senescence, nutrient mobilization, apical dominance, the formation and activity of shoot apical meristems, floral development, the breaking of bud dormancy, and seed germination.

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  • The major pathogenic mechanism of poststreptococcal glomerulonephritis (PSGN) is an in situ immune complex formation due to deposition of streptococcal nephritogenic antigens, such as nephritis-associated plasmin receptor (NAPlr) and Streptococcal pyrogenic exotoxin B (SPE B). Both are capable of activating the alternate pathway of the complement cascade and enhance the expression of adhesion molecules. SPE B also stimulates the production of chemotactic cytokines. NAPlr was isolated from group A streptococcus and was shown to bind plasmin(ogen).

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  • Cleavage of the amyloid precursor protein (APP) within the amyloid-beta (Ab) sequence by the a-secretase prevents the formation of toxic Abpep-tides. It has been shown that the disintegrin-metalloproteinases ADAM10 and TACE (ADAM17) act asa-secretases and stimulate the generation of a soluble neuroprotective fragment of APP, APPsa.

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  • The constraints of limited infrastructure and resources in most developing countries and the low level of awareness of opportunities for preventing the disease stimulated the formation in 1999 of the international Alliance for Cervical Cancer Prevention (ACCP), with funding from the Bill & Melinda Gates Foundation. The purposes of the ACCP are to develop and evaluate innovative approaches in order to reach more women at high risk of cervical cancer with effective and feasible screening and treatment services and to persuade policymakers and program managers to make it a priority.

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  • The goal of this study was to determine the effects of a putative specific cytosolic phospholipase A2 inhibitor, arachidonyl trifluoromethyl ketone (AACOCF3), on arachidonic acid (AA) release and lipid mediator biosynthesis by ionophore-stimulated human neutrophils. Initial studies indicated that AACOCF3 at concentrations 0–10 lM did not affect AA release from neutrophils. In contrast, AACOCF3 potently inhibited leukotriene B4 formation by ionophore-stimulated neutrophils (IC50  2.5 lM).

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  • This book presents a standard and relatively orthodox view of modern linguistic semantics in what we hope is a clear, stimulating, and accessible format. Our emphasis is on getting the student at every stage to think for himself, and so to proceed through the development of concepts in semantics with the confidence and conviction that comes from doing practical exercises with them. Inviting you to refer to part 2 of ebook.

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  • Purified recombinant proteins fromSynechocystisPCC6803 were used to show that the magnesium chelatase ChlH subunit stimulates magnesium protoporphyrin methyltransferase (ChlM) activity. Steady-state kinetics demonstrate that ChlH does not significantly alter theKmfor the tetrapyr-role substrate. However, quenched-flow analysis reveals that ChlH dramat-ically accelerates the formation and breakdown of an intermediate in the catalytic cycle of ChlM.

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  • The formation of disulfide bonds in the endoplasmic reti-culum requires protein disulfide isomerase (PDI) and endoplasmic reticulum oxidoreductin 1 (ERO1) that reoxi-dizes PDI. We report here that the expression of the rat, mouse andhumanhomologues ofERO1-Likeproteinabut not of the isoform ERO1-Lbare stimulated by hypoxia in rats vivo and in rat, mouse and human cell cultures.

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  • We describe a method for evaluating a grammar checking application with hand-bracketed parses. A randomly-selected set of sentences was submitted to a grammar checker in both bracketed and unbracketed formats. A comparison of the resulting error reports illuminates the relationship between the underlying performance of the parsergrammar system and the error critiques presented to the user.

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