Anyone who administers drugs acting on cardiovascular adrenergic mechanisms requires an understanding of how they act in order to use them to the best advantage and with safety. Adrenergic mechanisms Classification of sympathomimetics: by mode of action and selectivity for adrenoceptors Individual sympathomimetics Mucosal decongestants Shock Chronic orthostatic hypotension
Adrenaline, noradrenaline and dopamine are formed in the body and are used in therapeutics. The natural synthetic path is: tyrosine — dopa — dopamine — noradrenaline — adrenaline.
Pharmacology has undergone major intellectual changes in the recent years and has become
increasingly important to all medical, dental and other health professionals. The graduate
students of dentistry may have to handle medical emergency during various dental
procedures on the dental chair. Besides this, dentists have to look into various drug
associated interactions. The broad goal of teaching pharmacology to undergraduate
students is to inculcate rational and scientific basis of therapeutics keeping in view the
dental curriculum and profession.
Rhinitis medicamentosa (RM) is a condition that caused by overuse of topical nasal steroids. Also known as rebound or chemical rhinitis, the incidence is somewhere between 1-9% of non-allergic rhinitis and it is more common in younger adults and pregnant women.
To understand the cause of RM, we must first look at some of the basic science behind the nasal mucosa. The mucosa is innervated by sympathetic fiber that release norepinephrine, which stimulate alpha 1 and alpha 2 receptors. This in turns causes vasoconstriction.
(BQ) Part 2 book "Pharmacology for anaesthesia and intensive care" presents the following contents: Cardiovascular drugs (Sympathomimetics, adrenoceptor antagonists, anti-arrhythmics ,...), other important drugs (central nervous system, antiemetics and related drugs, drugs acting on the gut, intravenous fluids and minerals,...).