If your patient is critically ill with acute kidney injury (AKI), CRRT is one of the primary therapies. The goal of any continuous renal replacement therapy (CRRT) is to replace, as best as possible, the lost function of kidneys. CRRT provides slow and balanced fluid removal that even unstable patients - those with shock or severe fluid overload - can more easily tolerate. Both average and smaller size patients can undergo CRRT therapy and it can be adapted quickly to meet changing needs.
A variety of therapeutic interventions can help couples develop the tools for a successful relationship. Yet many practitioners begin seeing couples without extensive training in couples work. To fill this gap in their therapeutic repertoires, noted couples therapist Michele Harway brings together other well-known experts in marriage and family therapy to offer the Handbook of Couples Therapy, a comprehensive guide to the study and practice of couples therapy.
Therapy of Selected Diseases
crease in arteriolar resistance, ensuring adequate myocardial perfusion. During exercise, further dilation of arterioles is impossible. As a result, there is ischemia associated with pain. Pharmacological agents that act to dilate arterioles would thus be inappropriate because at rest they may divert blood from underperfused into healthy vascular regions on account of redundant arteriolar dilation. The resulting “steal effect” could provoke an anginal attack. (3) The intramyocardial pressure, i.e., systolic squeeze, compresses the capillary bed.
Quick Reference Dictionary for Massage Therapy and Bodywork will impress students and professionals in massage therapy as being a unique, ready reference for a wide variety of information relevant to the profession. Why look through numerous texts when everything you will want to find can be found inside one handy, pocket size resource?
The New Biology set consists of the following six volumes: The Cell,
Animal Cloning, Stem Cell Research, Gene Therapy, Cancer, and Aging.
The set is intended primarily for middle and high school students, but
it is also appropriate for first-year university students and the general
public. In writing this set, I have tried to balance the need for a comprehensive
presentation of the material, covering many complex fields,
against the danger of burying—and thereby losing—young students
under a mountain of detail.
Handbook of brief cognitive behaviour therapy discusses issues concerning the definition, the assessment, and, in particular,the practice of brief cognitive behaviour therapy (CBT. This book also considers the differences between brief and “regular” CBT, identifiescontraindications for the former, and summarises the empirical evidence of the efficacyof brief CBT. Finally, this book discusses an important professional issue in brief CBT:therapist burnout and how to avoid it certainly.
Harrison's Internal Medicine Chapter 65. Gene Therapy in Clinical Medicine
Gene Therapy in Clinical Medicine: Introduction
Gene transfer is a novel area of therapeutics in which the active agent is a nucleic acid sequence rather than a protein or small molecule. Because delivery of naked DNA or RNA to a cell is an inefficient process, most gene transfer is carried out using a vector, or gene delivery vehicle.
The general meaning of gene therapy is to correct defective genes that are responsible
for disease development. The most common form of gene therapy involves the
insertion, alteration or removal of genes within an individual's cells and biological
tissues. Many of gene transfer vectors are modified viruses. The ability for the delivery
of therapeutic genes made them desirable for engineering virus vector systems.
Recently, the viral vectors in laboratory and clinical use have been based on RNA and
DNA viruses processing very different genomic structures and host ranges.
Evidence-Based Counselling and Psychological Therapies assesses the
impact of the international drive towards evidence-based health care on
NHS policy and the provision of psychological services in the NHS.
An outstanding range of contributors provides an overview of
evidencebased health care and the research methods that underpin it,
demonstrating its effect on policy, provision, practitioners and patients.
In the last 10 years gene therapy has experienced a renascence thanks to the development of
safer and more efficient gene transfer vectors and to the advances in the cell therapy field.
This book brings together a comprehensive collection of gene therapy tools and their thera‐
peutic applications. The first part of the book covers different gene therapy vectors focusing
on their advantages and disadvantages.
Other Diseases The power and versatility of gene transfer approaches are such that there are few serious disease entities for which gene transfer therapies are not under development. Besides those already discussed, other areas of interest include gene therapies for HIV and for neurodegenerative disorders.
In the first section of this book, ‘Retroviral Vector’, chapter one discusses the efficiency
of retroviral DNA integration, the preferences of integration for certain regions, and
advances on integration site selection and gene therapy. Chapter two reviews and
discusses the current cell lines and bioreaction platforms used for production of
retroviral and lentiviral vectors, focusing on the current bottlenecks and future
directions with a particular emphasis in the metabolic constrains.
Harrison's Internal Medicine Chapter 107. Transfusion Biology and Therapy
Blood Group Antigens and Antibodies The study of red blood cell (RBC) antigens and antibodies forms the foundation of transfusion medicine. Serologic studies initially characterized these antigens, but now the molecular composition and structure of many are known. Antigens, either carbohydrate or protein, are assigned to a blood group system based on the structure and similarity of the determinant epitopes.
It has been said that the control of disease has three goals, which, in
increasing order of attraction are palliation, cure, and prevention. For most types
of disseminated cancer, medical science has achieved only the first of these
objectives, while for some malignancies the side effects of the therapeutic agents
employed rival the disease itself in precluding a desirable quality of life.
The basic precepts underlying previous editions of Clinical Drug Therapy continue to guide the
writing of this seventh edition. The overall purpose is to promote safe, effective, and rational drug
• Providing information that accurately reflects current practices in drug therapy.
• Facilitating the acquisition, comprehension, and application of knowledge related to drug
therapy. Application requires knowledge about the drug and the client receiving it.
Tham khảo sách 'recent advances in the biology, therapy and management of melanoma edited by lester m. davids', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả
Indications in gene therapy clinical trials. The chart divides clinical gene transfer studies by disease classification. A majority of trials have addressed cancer, with monogenic disorders and cardiovascular diseases the next largest
categories. (Reproduced with permission from J Gene Med. New Jersey, Wiley, 2006.)
Gene Transfer for Genetic Disease
Gene transfer strategies for genetic disease generally involve gene addition therapy. This approach most commonly involves transfer of the missing gene to a physiologically relevant target cell. ...
In patients with stable coronary artery disease, it remains unclear whether an initial
management strategy of percutaneous coronary intervention (PCI) with intensive
pharmacologic therapy and lifestyle intervention (optimal medical therapy) is superior
to optimal medical therapy alone in reducing the risk of cardiovascular events.
We conducted a randomized trial involving 2287 patients who had objective evidence
of myocardial ischemia and significant coronary artery disease at 50 U.S. and Canadian
Major advances have been accomplished in recent years in conformal and
stereotactic techniques, dosimetry as well as in target volume concepts, and
clinical studies have been performed. This peer-reviewed volume of Frontiers
of Radiation Therapy and Oncology includes a selection of the important
topics discussed at the meeting on ‘3-D Radiation Treatment: Technological
Innovations and Clinical Results’ which was organized by the Department of
Radiation-Oncology of the Technical University of Munich and focused on
conformal and stereotactic radiotherapy in the treatment of tumors....