Culture of Cells for Tissue Engineering is a new volume in the John Wiley series
Culture of Specialized Cells, with focus on procedures for obtaining, manipulating,
and using cell sources for tissue engineering. The book has been designed to follow
the successful tradition of other Wiley books from the same series, by selecting a
limited number of diverse, important, and successful tissue engineering systems and
providing both the general background and the detailed protocols for each tissue
During the last three decades, important advances have been made in the
available treatments for the loss of skeletal tissue as a result of trauma or
disease. The application of large skeletal allografts and total joint replacement
have become successful and reproducible treatment options. Unfortunately
there still is a significant incidence of failure because of mechanical or
The third edition of Principles of Tissue Engineering attempts to incorporate the latest advances in the biology and design of tissues and organs and simultaneously to connect the basic sciences — including new discoveries in the field of stem cells — with the potential application of tissue engineering to diseases affecting specific organ systems.
Harrison's Internal Medicine Chapter 69. Tissue Engineering
Tissue Engineering: Introduction The origins of tissue engineering date to the sixteenth century when complex skin flaps were used to replace the nose. Modern tissue engineering combines the disciplines of materials sciences and life sciences to replace a diseased or damaged organ with a living, functional substitute.
The most common tissue engineering approach combines cells and matrices to produce a living structure (Fig. 69-1).
Current clinical technologies, especially donor transplants and artificial organs, have
been excellent life-saving and life-extending therapies to treat patients who need
to reconstitute diseased or devastated organs or tissues as a result of an accident,
trauma, and cancer, or to correct congenital structural anomalies. For long, most
scientists and clinicians believed that damaged or lost tissues could only be replaced
by organ transplantation or with totally artificial parts.
A scaffold provides a three-dimensional framework to support the tissue or organ-specific cells. The scaffold not only provides mechanical support, but it must also supply critical nutrients and transport metabolites to and from the developing tissue. Important scaffold properties vary depending on the tissue but typically include specific biomechanical properties, porosity, biocompatibility, and appropriate surface characteristics for cell adhesion and differentiation.
Scaffolds can be natural materials or synthetic polymers and are typically biodegradable.
It is our pleasure to present this special volume on tissue engineering in the
series Advances in Biochemical Engineering and Biotechnology. This volume
reflects the emergence of tissue engineering as a core discipline of modern
biomedical engineering, and recognizes the growing synergies between the
technological developments in biotechnology and biomedicine. Along this
vein, the focus of this volume is to provide a biotechnology driven perspective
on cell engineering fundamentals while highlighting their significance in producing
Tuyển tập các báo cáo nghiên cứu khoa học ngành toán học được đăng trên tạp chí toán học quốc tế đề tài: Gelatin-layered and multi-sized porous beta-tricalcium phosphate for tissue engineering scaffold
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Gelatin-layered and multi-sized porous beta-tricalcium phosphate for tissue engineering scaffold
Advances in stem cell biology and biomaterials development in the late 1990s have helped
drive on an ever expanding body of research in the field of tissue engineering and regenerative
medicine. Scientists realized that the key to future success of functional tissues is bridging the gap
between developmental biology and tissue engineering. We are all amazed by the high degree of
sophistication and miniaturization found in nature. Nature is, indeed, a school of science.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Gene-enhanced tissue engineering for dental hard tissue regeneration: (1) overview and practical considerations
The origins of tissue engineering date to the sixteenth century when complex skin flaps were used to replace the nose. Modern tissue engineering combines the disciplines of materials sciences and life sciences to replace a diseased or damaged organ with a living, functional substitute. The most common tissue engineering approach combines cells and matrices to produce a living structure (Fig. 69-1). These strategies also include the use of scaffolding, cells, and growth factors to shape new tissues.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Quantitative ultrasound can assess the regeneration process of tissue-engineered cartilage using a complex between adherent bone marrow cells and a three-dimensional scaffold...