Vessel disease

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  • In Chapter 5, Carrascosa Romero and de Cabo de la Vega consider the relevance of genetics and brain imaging findings in the diagnosis of diseases which result from abnormal development or neoplasia of cells derived from the neural crest (neurocristopathies). Koga and Saito (Chapter 6) provide a beautifully illustrated discussion of the use of neuroimaging tools to guide gamma knife radiosurgery.

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  • For many years, the number one cause of death in the United States has been heart disease, which kills more than 650,000 people per year. In addition, almost 25 million people were living with a diagnosis of heart disease in 2004, according to the National Center for Health Statistics. The American Medical Association wants people to know and understand that aside from some inherited or congenital conditions, heart disease is largely preventable.

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  • Telangiectasias (Table 54-8) In order to distinguish the various types of telangiectasias, it is important to examine the shape and configuration of the dilated blood vessels. Linear telangiectasias are seen on the face of patients with actinically damaged skin and acne rosacea, and they are found on the legs of patients with venous hypertension and essential telangiectasia. Patients with an unusual form of mastocytosis (telangiectasia macularis eruptiva perstans) and the carcinoid syndrome (see "Acne," above) also have linear telangiectasias.

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  • Becoming less common. Poikiloderma is a term used to describe a patch of skin with (1) reticulated hypo- and hyperpigmentation, (2) wrinkling secondary to epidermal atrophy, and (3) telangiectasias. Poikiloderma does not imply a single disease entity—although becoming less common, it is seen in skin damaged by ionizing radiation as well as in patients with autoimmune connective tissue diseases, primarily dermatomyositis (DM), and rare genodermatoses (e.g., Kindler syndrome). In scleroderma, the dilated blood vessels have a unique configuration and are known as mat telangiectasias.

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  • Harrison's Internal Medicine Chapter 109. Disorders of Platelets and Vessel Wall Disorders of Platelets and Vessel Wall: Introduction Hemostasis is a dynamic process in which the platelet and the blood vessel wall play key roles. Platelets become activated upon adhesion to von Willebrand factor (vWF) and collagen in the exposed subendothelium after injury. Platelet activation is also mediated through shear forces imposed by blood flow itself, particularly in areas where the vessel wall is diseased, and is also affected by the inflammatory state of the endothelium.

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  • Tham khảo sách 'the nature of disease: pathology for the health professions_1', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • Pink Lesions The cutaneous lesions associated with primary systemic amyloidosis are often pink in color and translucent. Common locations are the face, especially the periorbital and perioral regions, and flexural areas. On biopsy, homogeneous deposits of amyloid are seen in the dermis and in the walls of blood vessels; the latter lead to an increase in vessel wall fragility. As a result, petechiae and purpura develop in clinically normal skin as well as in lesional skin following minor trauma, hence the term pinch purpura.

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  • Palpable purpura are further subdivided into vasculitic and embolic. In the group of vasculitic disorders, cutaneous small-vessel vasculitis, also known as leukocytoclastic vasculitis (LCV), is the one most commonly associated with palpable purpura (Chap. 319). Underlying etiologies include drugs (e.g., antibiotics), infections (e.g., hepatitis C virus), and autoimmune connective tissue diseases. Henoch-Schönlein purpura is a subtype of acute LCV that is seen primarily in children and adolescents following an upper respiratory infection.

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  • von Willebrand Disease vWD is the most common inherited bleeding disorder. Estimates from laboratory data suggest a prevalence of approximately 1%, but data based on symptomatic individuals suggest that it is closer to 0.1% of the population. vWF serves two roles: (1) as the major adhesion molecule that tethers the platelet to the exposed subendothelium; and (2) as the binding protein for FVIII, resulting in significant prolongation of the FVIII half-life in circulation.

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  • Since its introduction in the early 1970s, computed tomography (CT) has become a robust modality to evaluate extracranial, thoracic, and abdominal vascular distributions. It has become a gold standard to non-invasively image the aorta, pulmonary arteries, great vessels, renal and peripheral arteries. However, cardiac anatomy evaluation with this modality was not possible, due to rapid cardiac motion and slow image acquisition times.

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  • Volume 2 of the four-volume The Facts On File Encyclopedia of Health and Medicine presents the body systems that nourish, cleanse, and protect the body. These are the systems of cells and fluids and the structures that transport them throughout the body. Though distinct in their functions and purposes, these systems overlap and integrate with one another in inseparable ways. The Cardiovascular System Volume 2 opens with “The Cardiovascular System,” the structures and functions that carry blood throughout the body.

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  • It is only 26 years since the first percutaneous transluminal coronary angioplasty (PTCA) was carried out by the pioneering Swiss radiologist, Andreas Greuntzig, heralding the dawn of interventional cardiology. In this short time, interventional cardiology has overcome many limitations and undergone major evolutionary changes—most notably the development of the coronary stent. Worldwide, many thousands of patients now safely undergo percutaneous coronary intervention every day, and the numbers continue to grow.

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  • Pulmonary hypertension is characterized by a mediator imbalance with a predominance of vasoconstriction and cell proliferation involving all layers of the vessel. The end result is an increase in pulmonary vascular resistance, increased workload of the right ventricle, and right ventricular hypertrophy to maintain an adequate flow. Subsequently, right ventricular dilatation ensues the signs and symptoms of right heart failure occurence.

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  • Drinking and driving: It doesn’t take much alcohol to impair a person’s ability to drive. The chances of being killed in a single-vehicle crash are increased at a blood alcohol level that a 140-lb. woman would reach after having one drink on an empty stomach. Medication interactions: Alcohol can interact with a wide variety of medicines, both prescription and over-the-counter. Alcohol can reduce the effectiveness of some medications, and it can combine with other medications to cause or increase side effects.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study...

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  • joined the academic community after a career in private practice, the classroom was an alien place to me. I puzzled over the fact that the students I taught, who were of the very highest quality, still had trouble grasping the topics. I began to pay more critical attention to the textbooks I had selected for them, and I quickly learned the student perspective of most pathology texts: they are difficult to read. Most pathology books are compilations written by multiple authors, each with a certain writing style and with differing views about the relative importance of things.

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  • (BQ) Part 1 book "Diagnostic imaging spine" presentation of content: Congenital and genetic disorders, scoliosis and kyphosis, vertebral column, discs, and paraspinal muscle, cord, dura, and vessels, degenerative diseases, spondylolisthesis and spondylolysis, inflammatory, crystalline, and miscellaneous arthritides.

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  • Hemostasis is a dynamic process in which the platelet and the blood vessel wall play key roles. Platelets become activated upon adhesion to von Willebrand factor (vWF) and collagen in the exposed subendothelium after injury. Platelet activation is also mediated through shear forces imposed by blood flow itself, particularly in areas where the vessel wall is diseased, and is also affected by the inflammatory state of the endothelium.

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  • Angiogenesis is the development of new blood vessels from an existing vascular bed. Normal vascular proliferation occurs only during embryonic development, the female reproductive cycle, and wound repair. Many pathological conditions are characterized by persistent, unregulated angiogenesis, such as cancer, atherosclerosis, rheumatoid arthritis, and diabetic neuropathy. Conversely, inadequate angiogenesis can often lead to chronic pressure ulcers, duodenal ulcers, and myocardial infarction.

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  • Vasculitis, an inflammation of blood vessels, can be idiopathic or secondary to other conditions. Infections may also mimic idiopathic vasculitis, and the differential diagnosis is of paramount importance for the practicing physician. Vasculitides are not rare diseases. In fact, some vasculitides, such as giant cell arteritis, cutaneous vasculitis, and ANCA-associated vasculitis are relatively common in everyday practice. Vasculitis may rapidly lead to organ failure, and put patient's life in danger....

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