Violet staining

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  • Loss of tumor suppressors contributes to numerous cancer types. Many, but not all, proteins encoded by tumor suppressor genes have antiproliferative activity and halt cell-cycle progression. In this chapter, we present three methods that have been utilized to monitor the antimitogenic action exerted by tumor suppressors. Tumor suppressor function can be demonstrated by colony formation assays and acquisition of the flat-cell phenotype.

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  • Harrison's Internal Medicine Chapter 138. Moraxella Infections Moraxella catarrhalis The gram-negative coccus Moraxella catarrhalis is a component of the normal bacterial flora of the upper airways and has been increasingly recognized as a cause of otitis media, sinusitis, and bronchopulmonary infection. Over the past several decades, this organism has been variously designated as Micrococcus catarrhalis, Neisseria catarrhalis, and Branhamella catarrhalis. Bacteriology and Immunity On Gram's staining, M.

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  • Moraxella catarrhalis is a component of the normal bacterial flora of the upper airways and has been increasingly recognized as a cause of otitis media, sinusitis, and bronchopulmonary infection. Over the past several decades, this organism has been variously designated as Micrococcus catarrhalis, Neisseria catarrhalis, and Branhamella catarrhalis. Bacteriology and Immunity On Gram's staining, M. catarrhalis organisms appear as gram-negative cocci, sometimes occurring in pairs and having the side-by-side kidneybean configuration of Neisseria (Fig. 138-1).

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