The present text concerns the micro-level (particle-level) perspective on the different stages of the
granulation process. A range of the newest and advanced quantitative models is presented hereby
introducing recent advances in wetting and nucleation modelling, and theory describing granule
growth behaviour. The different bonding mechanisms and the strength of liquid bonded particles
are emphasised and recent advances in simulation of wet granule breakage is reviewed.
The present text introduces the use of fluidised bed processing in the context of wet granulation and
coating. The text also covers introductory information about the mechanical properties of dry granules.
This is a scientific field rarely taught at universities or engineering schools around the world although
it has enormous and ever increasing relevance to the chemical and biochemical industries. Often
students are left with nothing but qualitative tendencies and hands-on experience as no textbook yet
covers all relevant subjects treated in this text....
Introduction to hydrodynamic modelling and
The present text introduces hydrodynamic modelling principles in the context of batch wet
granulation and coating systems and it reviews the latest achievements and proposals in the
scientific literature in this field. The text concerns primarily the Eulerian and the Lagrangian
modelling technique. In accordance with some of the latest published Ph.d. thesis in the field of
hydrodynamics modelling, the Lagrangian technique is divided into a soft-particle and a hardsphere
The present text introduces the use of population balances in the context of batch wet granulation
and coating systems and it reviews the latest achievements and proposals in the scientific
literature in this field. The nature and framework of population balance theory are highlighted and
one-dimensional population balances are introduced from scratch. This may seems tedious at first
but the derivation of even the simplest population balances is nevertheless not an easy task, and it
is in fact difficult to find complete derivations elsewhere in literature.