Wet granules

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  • The present text concerns the micro-level (particle-level) perspective on the different stages of the granulation process. A range of the newest and advanced quantitative models is presented hereby introducing recent advances in wetting and nucleation modelling, and theory describing granule growth behaviour. The different bonding mechanisms and the strength of liquid bonded particles are emphasised and recent advances in simulation of wet granule breakage is reviewed.

    pdf62p tuanloc_do 04-12-2012 18 1   Download

  • The present text introduces the use of fluidised bed processing in the context of wet granulation and coating. The text also covers introductory information about the mechanical properties of dry granules. This is a scientific field rarely taught at universities or engineering schools around the world although it has enormous and ever increasing relevance to the chemical and biochemical industries. Often students are left with nothing but qualitative tendencies and hands-on experience as no textbook yet covers all relevant subjects treated in this text....

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  • Introduction to hydrodynamic modelling and granular dynamics The present text introduces hydrodynamic modelling principles in the context of batch wet granulation and coating systems and it reviews the latest achievements and proposals in the scientific literature in this field. The text concerns primarily the Eulerian and the Lagrangian modelling technique. In accordance with some of the latest published Ph.d. thesis in the field of hydrodynamics modelling, the Lagrangian technique is divided into a soft-particle and a hardsphere approach.

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  • The present text introduces the use of population balances in the context of batch wet granulation and coating systems and it reviews the latest achievements and proposals in the scientific literature in this field. The nature and framework of population balance theory are highlighted and one-dimensional population balances are introduced from scratch. This may seems tedious at first but the derivation of even the simplest population balances is nevertheless not an easy task, and it is in fact difficult to find complete derivations elsewhere in literature.

    pdf58p tuanloc_do 04-12-2012 14 1   Download

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