Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: tudies on Xenopus laevis intestine reveal biological pathways underlying vertebrate gut adaptation from embryo to adult...
channel KAT1 has been suggested to play a
key role in the regulation of the aperture of stomatal pores on the surface
of plant leaves. Calcium-dependent and calcium-independent signaling
pathways are involved in abscisic acid-mediated regulation of guard cell
turgidity. Although the activity of the KAT1 channel is thought to be regu-lated by calcium-dependent protein kinases, the effect of phosphorylation
on KAT1 and the phosphorylated target sites remain elusive.
Photolyase is a light-dependent enzyme that repairs pyrimidine dimers in
DNA. Two types of photolyases have been found in frogXenopus laevis,
one for repairing cyclobutane pyrimidine dimers (CPD photolyase) and
the other for pyrimidine–pyrimidone (6–4)photoproduct [(6–4)photolyase].
However, little is known about the former type of theXenopusphotolyases.
The Alzheimer’s disease-linked amyloid-bprecursor pro-tein (APP) belongs to a superfamily of proteins, which
also comprises the amyloid-b precursor-like proteins,
APLP1 and APLP2. Whereas APP has been identified in
both lower and higher vertebrates, thus far, APLP1 and 2
have been characterized only in human and rodents. Here
we identify the first nonmammalian APLP2 protein in the
South African claw-toed frogXenopus laevis.
Recent cloning of theXenopus laevis(Xl) matrix Gla protein (MGP) gene
indicated the presence of a conserved overall structure for this gene
between mammals and amphibians but identified an additional 5¢-exon, not
detected in mammals, flanked by a functional, calcium-sensitive promoter,
3042 bp distant from the ATG initiation codon.
To analyze the regulation of Matrix Gla Protein (MGP)
gene expression inXenopus laevis, we cloned the xMGPgene
and its 5¢ region, determined their molecular organization,
and characterized the transcriptional properties of the core
promoter. TheXenopusMGP (xMGP) gene is organized
into ®ve exons, one more as its mammalian counterparts.
The book Cell Interaction focuses on various processes that occur within and outside the cells. Cell interactions are important for functioning of many organ systems: cell adhesion, tissue development, cellular communication, inflammation, tumor metastasis, and microbial infection. Key features include developmental cell interactions, immune and neural cell interactions, cell interactions in normal and disease conditions and advanced level methods to evaluate cell interactions.
The caveolin gene family has three members in vertebrates: caveolin-1, caveolin-2, and caveolin-3. So far, most caveolin-related research has been conducted in mammals, but the proteins have also been found in other animals, including Xenopus laevis, Fugu rubripes, and Caenorhabditis elegans. Caveolins can serve as protein markers of caveolae (‘little caves’), invaginations in the plasma membrane 50-100 nanometers in
Thyrotropin-releasing hormone receptor (TRHR) has
already been cloned in mammals where thyrotropin-releas-inghormone (TRH) isknowntoactasapowerful stimulator
of thyroid-stimulating hormone (TSH) secretion. The TRH
receptor of amphibians has not yet been characterized,
although TRH is specifically important in the adaptation of
skin color to environmental changes via the secretion of
a-melanocyte-stimulating hormone (a-MSH).
Localization of a specific subset of maternal mRNAs to the vegetal cortex of
Xenopusoocytes is important for the regulation of germ layer formation and
germ cell development. It is driven by vegetal localization complexes that are
formed with the corresponding signal sequences in the untranslated regions
of the mRNAs and with a number of different so-called localization proteins.
Protein phosphatase 2A is a phosphoserine/threonine
phosphatase implicated inmany cellular processes. The core
enzyme comprises a catalytic and a PR65/A-subunit. The
substrate specificity and subcellular localization are deter-mined by a third regulatory B-subunit (PR55/B, PR61/B¢
and PR72/130/B¢¢). To identify the proteins of the B¢¢family
inXenopus laevisoocytes, aprophaseXenopusoocyte cDNA
librarywas screened using humanPR130 cDNAas a probe.
Three different classes of cDNAs were isolated....