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Báo cáo khoa học: Designing highly active siRNAs for therapeutic applications

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:8

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Báo cáo khoa học: Designing highly active siRNAs for therapeutic applications

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The discovery of RNA interference (RNAi) generated considerable interest in developing short interfering RNAs (siRNAs) for understanding basic biology and as the active agents in a new variety of therapeutics. Early studies showed that selecting an active siRNA was not as straightforward as simply picking a sequence on the target mRNA and synthesizing the siRNA complementary to that sequence.

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