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Chapter 136. Meningococcal Infections

Chia sẻ: Nguyen Nhi | Ngày: | Loại File: PDF | Số trang:19

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Chapter 136. Meningococcal Infections

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Neisseria meningitidis is the etiologic agent of two life-threatening diseases: meningococcal meningitis and fulminant meningococcemia. More rarely, meningococci cause pneumonia, septic arthritis, pericarditis, urethritis, and conjunctivitis. Most cases are potentially preventable by vaccination. Etiologic Agent Meningococci are gram-negative aerobic diplococci. Unlike the other neisseriae, they have a polysaccharide capsule. They are transmitted among humans—their only known habitat—via respiratory secretions. Colonization of the nasopharynx or pharynx is much more common than invasive disease. Microbiology and Classification On the basis of genome sequencing, N. meningitidis is categorized as a βproteobacterium related to Bordetella, Burkholderia, Kingella, and Methylomonas and—more distantly—to Vibrio, Haemophilus,...

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