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Comparative analysis of 14-3-3 isoform expression and epigenetic alterations in colorectal cancer

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Comparative analysis of 14-3-3 isoform expression and epigenetic alterations in colorectal cancer

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The 14-3-3 family is a group of intracellular proteins found in all eukaryotic organisms. Humans have seven isoforms that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes and previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers.

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Nội dung Text: Comparative analysis of 14-3-3 isoform expression and epigenetic alterations in colorectal cancer

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