EFFECTS OF INDOOR AIR POLLUTION ON HUMAN HEALTH

Exposure to carbon monoxide reduces maximum exercise ability in healthy young individuals and reduces the time to angina and, in some cases, the time to ST-segment depression in people with cardiovascular disease, albeit at a con- centration that is lower than that needed to reduce exercise ability in healthy in- dividuals. The relationship of carbon monoxide exposure and the carboxyhaemoglobin (COHb) concentration in blood can be modelled using the differential Coburn- Forster-Kane equation, which provides a good approximation to the COHb con- centration at a steady level of inhaled, exogenous carbon monoxide. Based on laboratory studies of reduction in exercise capacity in both healthy...