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Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data

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A fundamental fact in biology states that genes do not operate in isolation, and yet, methods that infer regulatory networks for single cell gene expression data have been slow to emerge. With single cell sequencing methods now becoming accessible, general network inference algorithms that were initially developed for data collected from bulk samples may not be suitable for single cells.

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Nội dung Text: Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data

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