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Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines

Chia sẻ: ViPutrajaya2711 ViPutrajaya2711 | Ngày: | Loại File: PDF | Số trang:11

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Wnt signaling has been linked with P-glycoprotein (P-gp) overexpression and which was mainly mediated by β-catenin nuclear translocation. Flavonoids have already been reported as modulators of the Wnt/βcatenin pathway and hence they may serve as promising agents in the reversal of P-gp mediated cancer multi drug resistance (MDR).

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Nội dung Text: Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines

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