Inhaled colistin for treatment of pneumonia due to multidrug-resistant gram-negative bacteria at a tertiary hospital, in Vietnam

There is a return of colistin as the treatment of last resort for multi-resistant bacteria. However, due to the limited penetration in the lung parenchyma and the renal side effects, the effectiveness of intravenous (IV) colistin therapy has been questioned. Colistin inhalation therapy is deemed tolerable, safe, and could be a beneficial therapy.