Pharmaceutical Coating Technology (Part 4)

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Pharmaceutical Coating Technology (Part 4)

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Solution properties and atomization in film coating Michael E.Aulton and Andrew M.Twitchell SUMMARY A little-considered stage of the film-coating process is the atomization of the coating solution by the spray gun. This chapter will show how formulation and process factors can cause marked changes in the characteristics of the spray, which may have important consequences for film formation and film properties. The chapter begins by describing how film-coating solution or suspension properties, such as density, surface tension and viscosity, alter with changing formulation and then continues by presenting predictions of how these properties could influence spray droplet size. The chapter...

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