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Unsupervised gene set testing based on random matrix theory

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Gene set testing, or pathway analysis, is a bioinformatics technique that performs statistical testing on biologically meaningful sets of genomic variables. Although originally developed for supervised analyses, i.e., to test the association between gene sets and an outcome variable, gene set testing also has important unsupervised applications, e.g., p-value weighting.

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Nội dung Text: Unsupervised gene set testing based on random matrix theory

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