Action and structure

This research achieved its objectives of: Identify key attributes and variables that influences the design of a PPP Project; Identify key actions and events that influence the outcomes generated by a PPP project; Model design attributes and variables, and actions and outcomes found in PPP literature; Evaluate Australian practice as demonstrated in a case study, using the benchmark model; Discuss findings and present conclusions.

146p runthenight04 02-02-2023 4 2   Download

Master's thesis of Science "Investigation into the modulation of circadian clock proteins by dietary compounds and small molecules" is structured as follows: Chapter 1 Introduction; Chapter 2 Identification of novel bioactive compounds from Olea europaea by evaluation of chemical compounds in the OliveNetTM library: in silico bioactivity and molecular modelling, and in vitro validation of hERG activity; Chapter 3 Modulation of circadian core clock proteins by dietary compounds; Chapter 4 Molecular mechanisms of action of selected olive phenolics against epigenetic modifiers and the structur...

235p runthenight04 02-02-2023 5 3   Download

"Master's thesis of Science: Intestinal permeability and functional properties of duodenal enteric neurons in a mouse model of autism" is structured as follows: Chapter 1: Introduction; Chapter 2: Measuring intestinal permeability in the Neuroligin-3R451C mouse model of autism; Chapter 3: Optimisation of the patch-clamp recording technique in the enteric nervous system to examine action potential characteristics in mouse duodenal myenteric neurons.

147p runthenight04 02-02-2023 11 4   Download

The thesis "Evaluating climate change mitigation and adaptation considerations in the Victorian planning system, Australia" is structured as follows: Chapter one: introduction; chapter two: climate change and the land use planning context: a review of literature; chapter three: policy and institutional framework for land use planning and climate change in Victoria; chapter four: research design; chapter five: assessing the state planning framework for awareness and analysis of climate change; chapter six: assessing local land-use implementation and action on climate change; chapter seven: c...

199p runthenight04 02-02-2023 9 4   Download

This action research was conducted with a view to understanding the influence of extensive reading on students‟ changed reading motivation. Extensive reading is believed to build up knowledge of vocabulary and structures for reading comprehension. It was hoped that when extensive reading was encouraged, students‟ reading motivation would change and their reading competence would be improved.

86p closefriend09 16-11-2021 32 5   Download

Research purpose: Clarifying some characteristics of the dialogue of notices responding to the communication of Nghe Tinh people in terms of structure and semantics. At the same time, aiming to point out some cultural characteristics of Nghe Tinh's behavior when realizing this dialogue. From there, orient the use of notification-response action in a theoretical and practical manner.

21p prisonbreak123 21-05-2021 11 2   Download

To establish the behavior model of the MIs and to employ this model to determine the seismic behavior of infilled frames; to study how to control the failure mechanisms of reinforced concrete (RC) frames under seismic actions, considering the interaction between the frame and the MIs.

27p kequaidan7 01-09-2020 30 2   Download

1. …can resist chemical action because it is corrosion-resistant. A. aluminum B. mild steel C.iron D. copper 2. The cross-section of a cylinder is…in shape. A. retangular B. circular C. square D. triangular 3. The post and lintel structure is … of straight members. A. consisted B. composed C. covered D. used 4. … materials can be used for structural support but not for dividing spaces. A. sheet B. rod C. block D. all 5. sheet materials are typically used for… construction buildings. A. mass B. frame C. planar D. primitive...

1p leaf_90 03-07-2013 130 15   Download

Agrobacterium tumefaciens is a Gram-negative, phytopathogenic bacterium and is characterized by an unique mode of action on dicotyledonous plants: it is able to genetically modify the host, and because of this feature, it is used as a tool for transgenic plants. Many experiments have demonstrated that lipopolysaccharides (LPSs) play an important role for the disease development, as they are involved in the adhesion process of the bacterium on the plant cell wall.

4p system191 01-06-2013 32 4   Download

Duodenase is a 29-kDa serine endopeptidase that displays selective trypsin- and chymotrypsin-like substrate specificity. This enzyme has been localized to epitheliocytes of Brunner’s glands, and as described here, to mast cells within the intestinal mucosa and lungworm-infected lung, implying an important additional role in inflammation and tissue remodelling. In primary cultures of pulmonary artery fibroblasts, duodenase induced a concentration-dependent increase in [3H]thymidine incorporation with a maximal effect observed at 30 nM.

10p research12 01-06-2013 53 3   Download

To Make an Interactive GUI Program To make an interactive GUI program, you need: Components buttons, windows, menus, etc. Events mouse clicked, window closed, button clicked, etc. Event listeners (interfaces) and event handlers (methods) listen for events to be trigged, and then perform actions to handle them

13p huanltgc00061 05-05-2013 53 5   Download

Hexadecylphosphocholine (HePC) is a synthetic lipid rep-resentative of a new group of antiproliferative agents, alkylphosphocholines (APC), which are promising candi-dates in anticancer therapy. Thus we have studied the action of HePC on the human hepatoblastoma cell line HepG2, which is frequently used as a model for studies into hepatic lipid metabolism.

7p research12 23-04-2013 42 1   Download

ThenblAfamily of genes encodes for small proteins neces-sary for the ordered degradation of phycobilisomes under certain stress conditions, a process known as chlorosis. Genes homologous tonblAseem to occur in all phycobili-some-containingorganisms.However, todate, nomolecular mechanism is known for the action of NblA, nor have the gene products been characterized to understand the physical properties of the molecule and thus help elucidate the mechanism on a structural basis.

8p research12 23-04-2013 45 4   Download

Serotonin transporters are key target sites for clinical drugs and psychostimulants, such as fluoxetine and cocaine. Molecular cloning of a serotonin transporter from the cen-tral nervous system of the insectManduca sextaenabled us to define domains that affect antagonist action, particularly cocaine.

11p research12 23-04-2013 35 1   Download

Microcin J25 (MccJ25) is the single macrocyclic antimicro-bial peptidebelonging to the ribosomally synthesizedclass of microcins that are secreted byEnterobacteriaceae.Itshowed potent antibacterial activity against severalSalmonellaand Escherichiastrains and exhibited a compact three-dimen-sional structure [Blondet al. (2001) Eur. J. Biochem., 268, 2124–2133]. The molecular mechanisms involved in the biosynthesis, folding andmode of action of MccJ25 are still unknown.

11p tumor12 22-04-2013 44 2   Download

Liver microsomal preparations are routinely used to predict drug interactions that can occurin vivo as a result of inhi-bition of cytochrome P450 (CYP)-mediated metabolism. However, the concentration of free drug (substrate and inhibitor)at its intrahepatic site of action, a variable that cannot be directly measured, may be significantly different from that in microsomal incubation systems.

10p tumor12 20-04-2013 47 4   Download

A100-kDa proteinwith endoglucanase activitywas purified from Triton X-100 extract of cells of the thermoacidophilic Gram-positive bacterium Alicyclobacillus acidocaldarius. The enzyme exhibited activity towards carboxy methyl cel-lulose and oat spelt xylan with pH and temperature optima of 4 and 80
C, respectively. Cloning and nucleotide sequence analysis of the corresponding gene (celB) revealed an ORF encoding a preprotein of 959 amino acids which is consistent with an extracellular localization.

10p tumor12 20-04-2013 33 2   Download

Ascorbic acid is often regarded as an antioxidantin vivo, where it protects against cancer by scavenging DNA-dam-aging reactive oxygen species. However, the detailed mech-anism of the action of ascorbic acid on genetic DNA is still unclear. We examined the effect of ascorbic acid on the higher-order structure of DNA through real-time observa-tion by fluorescence microscopy. We found that ascorbic acid generates a pearling structure in single giant DNA molecules, with elongated and compact regions coexisting along a molecular chain. ...

6p tumor12 20-04-2013 32 5   Download

A large number of bioactive peptides have been isolated from amphibian skin secretions. These peptides have a variety of actions including antibiotic and anticancer acti-vities and the inhibition of neuronal nitric oxide synthase. We have investigated the structure–activity relationship of citropin 1.1, a broad-spectrum antibiotic and anticancer agent that also causes inhibition of neuronal nitric oxide synthase, by making a number of synthetically modified analogues.

13p tumor12 20-04-2013 37 3   Download

Sequence analysis of aPaenibacillussp. BP-23 recombinant clone coding for a previously described endoglucanase revealed the presence of an additional truncated ORF with homology to family 48 glycosyl hydrolases. The corres-ponding 3509-bp DNA fragment was isolated after gene walking and cloned inEscherichia coliXl1-Blue for expres-sion and purification. The encoded enzyme, a cellulase of 1091 amino acids with a deduced molecular mass of 118 kDa and a pI of 4.

7p fptmusic 16-04-2013 50 3   Download