Xem 1-12 trên 12 kết quả Amphiphiles
  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Self assembly of amphiphilic C60 fullerene derivatives into nanoscale supramolecular structures

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  • The molecular self-assembly is induced by variation in the surroundings, such as temperature [1-4], pressure [5-9], pH [10-14], salt formation [13-18], and noncovalent bond cross-linking [19- 21]. The block copolymers are molecularly converted in situ from the nonamphiphilic copolymers completely dissolved in a solvent to amphiphilic copolymers due to these stimuli. Therefore, the association and dissociation of the isolated copolymers are reversibly controlled by such stimuli.

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  • The C-terminal t peptide (40 residues) of vertebrate acetyl-cholinesterase (AChE) T subunits possesses a series of seven conserved aromatic residues and forms an amphiphilic a-helix; it allows the formation of homo-oligomers (mono-mers, dimers and tetramers) and heteromeric associations with the anchoringproteins, ColQ and PRiMA, which contain a proline-rich motif (PRAD). We analyzed the influenceofmutations in the t peptideofTorpedoAChETon oligomerization and secretion.

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  • Trong nghiên cứu này tác giả giới thiệu các kết quả về tính chất thấm ớt của bề mặt polyuretan ghép thông qua xác định góc tiếp xúc, khả năng hút nước và tính chất cơ học của chúng.

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  • Vibrio choleraehemolysin (HlyA), a water-soluble protein with a native monomeric relative molecular mass of 65 000, forms transmembrane pentameric channels in target bio-membranes.TheHlyAbinds to lipid vesicles nonspecifically and without saturation; however, self-assembly is triggered specifically by cholesterol.Here we show that the HlyA partitioned quantitatively to amphiphilic media irrespective of their compositions, indicating that the toxin had an amphiphilic surface.

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  • Semi-intact cells are cells whose plasma membrane has been permeabilized with detergent or toxins, and can be referred to as “cell-type test tubes” (Fig. 1). We use a bacterial poreforming toxin, streptolysin O (SLO), to permeabilize the cells. At 4℃, SLO binds to cholesterol in plasma membranes. At warmer temperatures, SLO assembles to form amphiphilic oligomers, which results in the generation of small, stable transmembrane pores (Bhakdi et al., 1985).

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  • Nanotechnology has received tremendous interest over the last decade, not only from the scientific community but also from a business perspective and from the general public. Although nanotechnology is still at the largely unexplored frontier of science, it has the potential for extremely exciting technological innovations that will have an enormous impact on areas as diverse as information technology, medicine, energy supply and probably many others. The miniaturization of devices and structures will impact the speed of devices and information storage capacity.

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  • Soft matter (or soft condensed matter) refers to a group of systems that includes polymers, colloids, amphiphiles, membranes, micelles, emulsions, dendrimers, liquid crystals, polyelectrolytes, and their mixtures. Soft matter systems usually have structural length scales in the region from a nanometer to several hundred nanometers and thus fall within the domain of “nanotechnology.” The soft matter length scales are often characterized by interactions that are of the order of thermal energies so that relatively small perturbations can cause dramatic structural changes in them.

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  • Polyurethanes are block copolymers composed of alternating short hard segments and long flexible soft segments that are thermodynamically incompatible at the temperature of use [1,2]. Phase separation of segmented polyurethanes (SPU) with a limited hard segment content results in hard segment rich domains dispersed in a continuous matrix of the soft segments [3]. The hard domains act as physical crosslink providing the polymer with mechanical strength while the soft matrix contributes to the elastomeric properties [4,5]....

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  • AP1 (GEQGALAQFGEWL) was shown by theoretical analysis to be an anionic oblique-orientateda-helix former. The peptide exhibited a mono-layer surface area of 1.42 nm 2 , implying possession of a-helical structure at an air⁄water interface, and Fourier transform infrared spectroscopy (FTIR) showed the peptide to be a-helical (100%) in the presence of vesi-cle mimics of Escherichia colimembranes.

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  • Acetylcholinesterase subunits of type T (AChET) possess an alternatively spliced C-terminal peptide (t peptide) which endows them with amphiphilic properties, the capacity to form various homo-oligomers and to associate, as a tetra-mer, with anchoring proteins containing a proline rich attachment domain (PRAD). The t peptide contains seven conserved aromatic residues.

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  • Glycosylatedpolyenemacrolide antibiotics, as nystatins and amphotericins, are amphiphilic structures known to exert antifungal activity by disrupting the fungal cell membrane, leading to leakage of cellular materials, and cell death. This membrane disruption is strongly influenced by the presence and the exact nature of the membrane sterols.

    pdf9p research12 23-04-2013 13 1   Download


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