Biological mechanisms

To evaluate the outcomes of whole-brain radiotherapy (WBRT) in patients with brain metastases from non-lung cancer at Viet Tiep Friendship Hospital between January 2022 and December 2023.

5p vibecca 01-10-2024 2 2   Download

This study aimed to investigate the possibility of degrading the pesticides of the BAC process. Based on the promising results in the full-scale reactor receiving river water, a lab-scale reactor was installed to study the pesticide removal mechanism and the contribution of nitrifying bacteria to the removal efficiency.

13p vifilm 24-09-2024 2 1   Download

Master's thesis of Science "Investigation into the modulation of circadian clock proteins by dietary compounds and small molecules" is structured as follows: Chapter 1 Introduction; Chapter 2 Identification of novel bioactive compounds from Olea europaea by evaluation of chemical compounds in the OliveNetTM library: in silico bioactivity and molecular modelling, and in vitro validation of hERG activity; Chapter 3 Modulation of circadian core clock proteins by dietary compounds; Chapter 4 Molecular mechanisms of action of selected olive phenolics against epigenetic modifiers and the structur...

235p runthenight04 02-02-2023 5 3   Download

The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the interdependence of transcription initiation, splicing and polyadenylation events on single mRNA molecules by full-length mRNA sequencing.

18p vimichaelfaraday 25-03-2022 16 2   Download

Animals can show very different behaviors even in isogenic populations, but the underlying mechanisms to generate this variability remain elusive. We use the zebrafish (Danio rerio) as a model to test the influence of histone modifications on behavior.

21p vimichaelfaraday 25-03-2022 13 1   Download

Chromatin state provides a clear decipherable blueprint for maintenance of transcriptional patterns, exemplifying a mitotically stable form of cellular programming in dividing cells. In this regard, genomic studies of chromatin states within cancerous tissues have the potential to uncover novel aspects of tumor biology and unique mechanisms associated with disease phenotypes and outcomes.

15p vielonmusk 21-01-2022 14 1   Download

Heterogeneous nuclear ribonucleoprotein (HNRNP) A1 and A2 are the most abundant HNRNPs with nearly identical functions, and play important roles in regulating gene expression at multiple levels (i.e. transcription, posttranscription, and translation). However, the expression and regulation mechanism of HNRNPA1 and A2 themselves remain unclear. In this study, the amino acid sequences of HNRNPA1 and HNRNPA2 were compared and found to have 78% and 86% homology in key functional domains.

10p thiencuuchu 27-11-2021 10 1   Download

Autophagy and DNA repair are two essential biological mechanisms that maintain cellular homeostasis. Impairment of these mechanisms was associated with several pathologies such as premature aging, neurodegenerative diseases, and cancer. Intrinsic or extrinsic stress stimuli (e.g., reactive oxygen species or ionizing radiation) cause DNA damage. As a biological stress response, autophagy is activated following insults that threaten DNA integrity.

18p thiencuuchu 27-11-2021 11 1   Download

Molecular knowledge regarding the primary esophageal achalasia is essential for the early diagnosis and treatment of this neurodegenerative motility disorder. Therefore, there is a need to find the main microRNAs (miRNAs) contributing to the mechanisms of achalasia. This study was conducted to determine some patterns of deregulated miRNAs in achalasia. This case-control study was performed on 52 patients with achalasia and 50 nonachalasia controls. The miRNA expression profiling was conducted on the esophageal tissue samples using the next-generation sequencing (NGS).

13p thiencuuchu 27-11-2021 9 2   Download

Nicotinamide N-methyltransferase (NNMT), a key cytoplasmic protein in the human body, is accountable to catalyze the nicotinamide (NCA) N1 -methylation through S-adenosyl-L-methionine (SAM) as a methyl donor, which has been linked to many diseases. Although extensive studies have concerned about the biological aspect, the detailed mechanism study of the enzyme function, especially in the part of protein dynamics is lacking.

9p thiencuuchu 27-11-2021 17 2   Download

In Vietnam, lotus plants are widely grown. Some parts of the lotus plant have been used as a tradition medicine. The lotus plant is easy to find, inexpensive, non-toxic and accepted by many Vietnamese people as a means of treating diabetes, and yet data on the mechanism or even effectiveness of lotus leaf on diabetes mellitus was not known. The present study was designed to evaluate the hypoglycemic effect of lotus leaf on mice which had alloxan induced diabetes.

10p tamynhan8 04-11-2020 16 3   Download

The study was carried out during 2013-14 in Meerut district of Uttar Pradesh state to focus on the sugarcane growers regarding impact of knowledge on adoption level of IPM practices. The 80 contact farmers were selected as respondents. The study revealed that the maximum knowledge gap was found to be existing in previous crop residues, crop rotation, hand picking of the insect and their destruction, hot air and water treatment, light and pheromone trap, microbial control, use of natural enemies, resistant varieties, biopesticides/ bio-agents, application and dose of different pest etc.

7p chauchaungayxua6 26-06-2020 20 3   Download

In vivo haploid induction (HI) based on Stock6-derived inducer lines has been the most prevalent means of producing haploids. Nevertheless, the biological mechanism of HI is not fully understood, the twinembryo kernels had been found during haploid induction, which may provide potential evidence for the abnormal double fertilization during HI.

9p vishikamaru2711 29-04-2020 12 1   Download

Phosphorus (Pi) deficiency induces root morphological remodeling in plants. The primary root length of rice increased under Pi deficiency stress; however, the underlying mechanism is not well understood.

14p vishikamaru2711 29-04-2020 16 1   Download

The anther cuticle, which is primarily composed of lipid polymers, is crucial for pollen development and plays important roles in sexual reproduction in higher plants. However, the mechanism underlying the biosynthesis of lipid polymers in maize (Zea mays. L.) remains unclear.

14p vishikamaru2711 29-04-2020 14 1   Download

Rapeseed (Brassica napus L.) and soybean (Glycine max L.) seeds are rich in both protein and oil, which are major sources of biofuels and nutrition. Although the difference in seed oil content between soybean (~ 20%) and rapeseed (~ 40%) exists, little is known about its underlying molecular mechanism.

15p vishikamaru2711 29-04-2020 11 0   Download

Increasing the productivity of rapeseed as one of the widely cultivated oil crops in the world is of upmost importance. As flowering time and plant architecture play a key role in the regulation of rapeseed yield, understanding the genetic mechanism underlying these traits can boost the rapeseed breeding

12p vishikamaru2711 29-04-2020 16 1   Download

Trichoderma species, a class of plant beneficial fungi, may provide opportunistic symbionts to induce plant tolerance to abiotic stresses. Here, we determined the possible mechanisms responsible for the indole acetic acid (IAA) and 1-aminocyclopropane-1-carboxylate-deaminase (ACC-deaminase) producing strain of Trichoderma longibrachiatum T6 (TL-6) in promoting wheat (Triticum aestivum L.) growth and enhancing plant tolerance to NaCl stress.

18p vishikamaru2711 29-04-2020 13 1   Download

Among various pests, the brown planthopper (BPH) that damages rice is the major destructive pests. Understanding resistance mechanisms is a critical step toward effective control of BPH.

11p vishikamaru2711 29-04-2020 10 0   Download

Research objectives: It is to determine agrobiological features as a scientific basis for the study of the mechanism creating seedless fruits, and to intervene with technical measures in order to improve productivity and quality of fruits of citrus trees. It is to study applications of some technical measures to improve productivity and quality of fruits in some citrus tree cultivars.

27p change03 06-05-2016 45 4   Download