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Cancer gene prediction

Xem 1-14 trên 14 kết quả Cancer gene prediction
  • (bq) part 2 book “cancer systems biology” has contents: cancer gene prediction using a network approach, cancer genomics to cancer biology, tumors and their microenvironments, gene set and pathway-based analysis for cancer omics,… and other contents.

    pdf204p tieu_vu15 07-09-2018 19 0   Download

  • Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Survivin gene levels in the peripheral blood of patients with gastric cancer independently predict survival

    pdf8p dauphong3 03-01-2012 57 4   Download

  • Bioinformatics is at a crossroads. We work in a field that is changing every day, increasingly moving from specific solutions created by single researchers working alone or in small groups to larger, often geographically dispersed programs enabled by collaborative computing and open software. This book represents an important development, giving the reader an opportunity to discover how the use of open and reusable Java code can solve large bioinformatics problems in a software engineered and robust way.

    pdf353p echbuon 02-11-2012 50 8   Download

  • Breast cancer (BC), the most common type of cancer among women worldwide, is a polygenetic disease which is caused by the interaction of several genes. Understanding the genetic factors for early diagnosis of BC is crucial to ensure the survival of BC patients. MicroRNA 27a (miR-27a), an oncogenic miRNA, has been predicted to target on the tumor suppressor ZBTB10 that can regulate many processes of cell.

    pdf11p bautroibinhyen17 13-02-2017 24 2   Download

  • Further, Mamede and Schmidt (2004) found that reflective practice in medicine in their study had a five-factor structure: deliberate induction, which involves the physician taking time to reflect upon an unfamiliar problem; deliberate deduction, which occurs when a physician logically deduces the consequences of a number of possible hypotheses; testing, which involves evaluating predictions against the problem being explored; openness to reflection, occurring when a physician is willing to engage in such constructive activity when faced with an unfamiliar situation; and, meta-reasoning, w...

    pdf11p thangbienthai 17-11-2012 28 0   Download

  • Clinical course of CLL is variable. Recently, progress has been made in the identification of biological markers that could predict disease progression. Particularly, the expression of unmutated Ig genes, some cytogenetic abnormalities like 17p and 11q deletions and the expression of the zeta-associated protein 70 (ZAP-70) are associated to a poor prognosis.

    pdf458p wawawawawa 26-07-2012 61 11   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?

    pdf4p panasonic02 15-12-2011 44 2   Download

  • In the nematodeCaenorhabditis elegans, 40 genes code for astacin-likeproteins (nematodeastacins,NAS).The astacins are metalloproteases present in bacteria, invertebrates and vertebrates and serve avarietyof physiological functions like digestion, hatching, peptide processing, morphogenesis and pattern formation. With the exception of one distorted pseudogene, all the otherC. elegansastacins are expressed and are evidently functional. For 13 genes we found splicing patterns differing from the Genefinder predictions in WormBase, sometimes markedly....

    pdf12p fptmusic 12-04-2013 25 2   Download

  • EDRN is a leader in defining and using criteria for the validation of biomarkers—an essential condition for scientific progress. While myriad proteins and genes have been linked with a variety of cancers, acceptable biomarkers must be: reliable and repeatable in testing; highly sensitive and specific; quantitative; readily obtained by non-invasive methods; part of the causal pathway for disease; capable of being modulated by the che- mopreventive agent; and have high predictive value for clinical disease.

    pdf0p khongmuonnghe 07-01-2013 31 1   Download

  • A method has been developed to predict the effects of mutations in the p53 cancer suppressor gene. The new method uses novel parameters combined with previously established parameters. The most important parameter is the stability measure of the mutated structure calculated using molecular modelling.

    pdf14p vinaphone15 25-02-2013 21 1   Download

  • Mammalian glycerol uptake⁄transporter 1 (Gup1), a homolog of Saccharo-myces cerevisiaeGup1, is predicted to be a member of the membrane-boundO-acyltransferase family and is highly homologous to mammalian hedgehog acyltransferase, known as Skn, the homolog of the Drosoph-ila skinny hedgehog gene product.

    pdf14p media19 05-03-2013 30 1   Download

  • The gene encompassing ORF Rv1885c with weak sequence similarity to AroQ chorismate mutases (CMs) was cloned from the genome ofMycobac-terium tuberculosis and expressed in Escherichia coli. The gene product (*MtCM) complements a CM-deficient E. colistrain, but only if produced without the predicted N-terminal signal sequence typical ofM. tuberculosis. The mature *MtCM, which was purified by exploiting its resistance to irre-versible thermal denaturation, possesses high CM activity in vitro.

    pdf15p awards 05-04-2013 28 1   Download

  • In practice, signatures that predict toxicity or efficacy can be identified afterwards. For example, therapies targeting the Epidermal Growth Factor Receptor have been first approved before it was demonstrated that mutations in KRAS cancer gene were associated to failures of the relevant therapies in metastatic colorectal carcinoma. This example shows that well-designed retrospective analysis of data from prospective randomized controlled trials can bring forward effective treatments to biomarker defined subgroups of patients in a timely manner.

    pdf16p quynho77 14-11-2012 30 0   Download

  • Urokinase-type plasminogen activator (uPA) and c-met play a major role in cancer invasion and metastasis. Evidence has suggested that uPA and c-met overexpression may be coordinated in human hepatocellular carci-noma (HCC). In the present study, to understand whether the expression of these genes might be coregulated by specific microRNAs (miRs) in human cells, we predicted thatHomo sapiensmicroRNA-23b could recog-nize two sites in the 3¢-UTR of uPA and four sites in the c-met 3¢-UTR by the algorithm pictar. ...

    pdf17p viettel02 22-02-2013 29 1   Download

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