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Cancer genomics

Xem 1-20 trên 123 kết quả Cancer genomics
  • (bq) part 2 book “cancer systems biology” has contents: cancer gene prediction using a network approach, cancer genomics to cancer biology, tumors and their microenvironments, gene set and pathway-based analysis for cancer omics,… and other contents.

    pdf204p tieu_vu15 07-09-2018 19 0   Download

  • Today, cancer research is focused on determining how genome and proteome level information may be useful as tools in prevention, diagnosis, and prognosis. The development of “omics” technologies, such as proteomics and transcriptomics has opened new research areas for scientists working on cancer research.

    pdf238p lyly_5 22-03-2013 44 6   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Probing the cancer genome...

    pdf3p coxanh_8 05-11-2011 32 3   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Prostate cancer genomics: can we distinguish between indolent and fatal disease using genetic markers?

    pdf7p panasonic02 15-12-2011 26 3   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Cancer genomics identifies determinants of tumor biology...

    pdf0p thulanh22 20-11-2011 46 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Environmental exposures and mutational patterns of cancer genomes

    pdf4p panasonic02 15-12-2011 37 2   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays...

    pdf0p thulanh21 15-11-2011 29 1   Download

  • (BQ) Continued part 1, part 2 of the document Cancer in the biology (Second edition) has contents: Multi-Step tumorigenesis, maintenance of genomic integrity and the development of cancer, the rational treatment of cancer, crowd control - tumor immunology and immunotherapy,... and other contents. Invite you to refer.

    pdf611p thuongdanguyetan06 06-06-2019 3 0   Download

  • Oncogenes in Human Cancer Oncogenes of the kind found in human cancers were initially discovered through their presence in the genome of retroviruses capable of causing cancers in chickens, mice, and rats. The cellular homologues of these viral genes are often targets of mutation or aberrant regulation in human cancer. Whereas many oncogenes were discovered because of their presence in retroviruses, other oncogenes, particularly those involved in translocations characteristic of particular leukemias and lymphomas, were isolated through genomic approaches.

    pdf5p konheokonmummim 03-12-2010 58 5   Download

  • This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence.

    pdf496p phoebe75 19-02-2013 39 5   Download

  • Cells respond to environmental cues through a complex and dynamic network of signaling pathways that normally maintain a critical balance between cellular proliferation, differentiation, senescence, and death. One current research challenge is to identify those aberrations in signal transduction that directly contribute to a loss of this division-limited equilibrium and the progression to malignant transformation. The study of cell-signaling molecules in this context is a central component of cancer research.

    pdf349p spy107 11-10-2012 40 4   Download

  • Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition.

    pdf251p tom_123 15-11-2012 38 4   Download

  • Acetylation of the amino terminus of the core histones H3 and H4 induces an open chromatin conformation that promotes transcription initiation. Histone acetylases are components of coactivator complexes recruited to promoter/enhancer regions by sequence-specific transcription factors during the activation of genes (Fig. 80-4). Histone deacetylases (HDACs; at least 17 are encoded in the human genome) are recruited to genes by transcriptional repressors and prevent the initiation of gene transcription.

    pdf5p konheokonmummim 03-12-2010 40 3   Download

  • Most (78%) mitochondrial genomes in the studied mutant strain of Drosophila subobscura have undergone a large-scale deletion (5 kb) in the coding region. This mutation is stable, and is transmitted intact to the offspring. This animal model of major rearrangements of mitochondrial genomes can be used to analyse the involvement of the nuclear genome in the production and maintenance of these rearrangements.

    pdf8p research12 01-06-2013 32 3   Download

  • Last decade major advances have been made in the field of mouse model engineering. Newly developed conditional mouse models have overcome important drawbacks in conventional mouse models. Conditional mouse models are especially suited for the development of models of sporadic human carcinomas. These models can control gene (in)activation in a time and/or tissue-specific manner. Here, we review two important conditional mouse model systems, based on the Tet off/on and the Cre-Lox system.

    pdf215p tom_123 15-11-2012 29 2   Download

  • The current literature suggests that approximately half to two thirds of those diag- nosed with breast cancer handle it well psychologically (Baker, Marcellus, Zabora, Pol- land, Jodrey, 1997; Spiegel, 1996). In fact, some individuals with a history of cancer report renewed vigor in their approach to life, and stronger interpersonal relationships (Anderson, 1986; Cella & Tross, 1986). For example, Tempelaar and colleagues (1989) found that cancer patients reported more positive and fewer negative social experiences than a comparison group of healthy “normals.

    pdf14p taisaokhongthedung 09-01-2013 35 2   Download

  • Homeobox genes play a critical role in regulating various aspects of plant growth and development. In the present study, we identified a total of 107 homeobox genes in the rice genome and grouped them into ten distinct subfamilies based upon their domain composition and phylogenetic analy-sis.

    pdf17p media19 06-03-2013 29 2   Download

  • Licensing origins for replication upon completion of mitosis ensures genomic stability in cycling cells. Cdt1 was recently discovered as an essential licensing factor, which is inhibited by geminin. Over-expression of Cdt1 was shown to predis-pose cells for malignant transformation. We show here that Cdt1 is down-regulated at both the protein and RNA level when primary human fibroblasts exit the cell cycle into G0, and its expression is induced as cells re-enter the cell cycle, prior to S phase onset. ...

    pdf11p awards 05-04-2013 19 2   Download

  • TheNS5Bproteinof the classical swine fever virus (CSFV) is the RNA-dependent RNA polymerase of the virus and is able to catalyze the viral genome replication. The 3¢ un-translated region is most likely involved in regulation of the Pestivirusgenome replication. However, little is known about the interaction between the CSFV NS5B protein and the viral genome.We used different RNA templates derived fromthe plus-strand viral genome, or theminus-strand viral genome and the CSFV NS5B protein obtained from the Escherichia coliexpression system to address this problem....

    pdf9p awards 05-04-2013 22 2   Download

  • Chapter 17 - Somatic mutation and the genetics of cancer. The genetics of cancer are clearly more complex than most of the other diseases. In this chapter, we attempt to answer some basic questions about this topic that hopefully will help put the chapters on cancer in perspective and explain their organization.

    ppt53p tangtuy04 12-03-2016 35 2   Download

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