Cellular and molecular basis

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  • (BQ) Part 1 of the document Ganong's review of medical physiology presents the following contents: Cellular and molecular basis for medical physiology, central and peripheral neurophysiology, endocrine and reproductive physiology.

    pdf463p thangnamvoiva3 01-07-2016 39 9   Download

  • (BQ) Part 1 of the document Ganong's review of medical physiology presents the following contents: Cellular and molecular basis for medical physiology, central and peripheral neurophysiology, endocrine and reproductive physiology.

    pdf463p thangnamvoiva3 01-07-2016 27 3   Download

  • Heart disease is one of the largest causes of death in humans throughout the developed world. Despite its critical role in maintaining physiologic homeostasis, the adult mammalian heart does not exhibit a significant capacity for regeneration.

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  • part 1 book “general and molecular pharmacology” has contents: essential lexicon of pharmacology, a short history of pharmacology, cellular basis of pharmacokinetics , drug absorption and administration routes, drug distribution and elimination, drug metabolism.

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  • (bq) part 1 book "management of cardiac arrhythmias" presents the following contents: introduction (management of ventricular arrhythmias - an historical perspective, history of supraventricular tachycardia), cardiac electrophysiology (ionic and cellular basis for arrhythmogenesis, genetic and molecular basis of arrhythmias), diagnostic testing.

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  • Human dynein light chain 1 (DYNLL1) is a dimeric 89-residue protein that is known to be involved in cargo binding within the dynein multiprotein complex. Over 20 protein targets, of both cellular and viral origin, have been shown to interact with DYNLL1, and some of them are transported in a retrograde manner along microtubules.

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  • Since the discovery of the DNA structure researchers have been highly interested in the molecular basis of genome inheritance. This book covers a wide range of aspects and issues related to the field of DNA replication. The association between genome replication, repair and recombination is also addressed, as well as summaries of recent work of the replication cycles of prokaryotic and eukaryotic viruses. The reader will gain an overview of our current understanding of DNA replication and related cellular processes, and useful resources for further reading....

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  • The biochemical nature and the replication of infectious prions have been intensively studied in recent years. Much less is known about the cellular events underlying neuronal dysfunction and cell death. As the cellular func-tion of the normal cellular isoform of prion protein is not exactly known, the impact of gain of toxic function or loss of function, or a combination of both, in prion pathology is still controversial.

    pdf6p galaxyss3 21-03-2013 35 4   Download

  • Welcome to the home of the online edition of The Cancer Handbook which provides a comprehensive overview of all major areas of cancer research and oncology. This title differs from existing oncology textbooks and reference works in that it bridges the gap between the molecular biology of cancer and clinical diagnosis and treatment. As more and more laboratory research is applied to clinical management, e.g. the use of monoclonal antibodies as drugs, it is important that clinicians understand the aetiology of the disease and the molecular basis of the new therapeutic approaches. ...

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  • An ultimate goal of modern biology is to understand how the genetic blueprint of cells (genotype) determines the structure, function, and behavior of a living organism (phenotype). At the center of this scientific endeavor is characterizing the biochemical and cellular roles of proteins, the working molecules of the machinery of life. A key to understanding of functional proteins is the knowledge of their folded structures in a cell, as the structures provide the basis for studying proteins’ functions and functional mechanisms at the molecular level....

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  • Nowadays, with over a thousand bacterial genomes sequenced, even greater opportunities have opened for experimental or computational global analysis of metabolism, physiology, and evolution. In particular, the access to comprehensive sets of molecular components (genes, proteins, regulatory signals) is at the basis of the development of novel integrative approaches, aiming at understanding the function of specific sets of these components (operons, regulons, metabolic pathways, protein complexes, etc.) in the context of the whole organism.

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  • The occurrence of DNA double-strand breaks in the nucleus provokes in its structural organization a large-scale alteration whose molecular basis is still mostly unclear. Here, we show that double-strand breaks trigger pref-erential assembly of nucleoproteins in human cellular fractions and that they mediate the separation of large protein–DNA aggregates from aque-ous solution.

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  • (BQ) Part 1 of the document Principles of genetics presents the following contents: The science of genetics, cellular reproduction, mendelism the basic principles of inheritance, extensions of mendelism, the chromosomal basis of mendelism, variation in chromosome number and structure, the genetics of bacteria and their viruses, DNA and the molecular structure of chromosomes,... and other content.

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