Emerging diseases

The article presented a case of bacteremia caused by Chromobacterium violaceum in a 9-year-old girl. This was a rare disease in humans, so the diagnosis and treatment were delayed. The entire prossess of disease and antibiotic therapy have been described in detail. Although life was saved, the consequences for the patient can be long-lasting.

6p vifaye 20-09-2024 2 1   Download

Febrile convulsions are a fairly common emergency in children, accounting for up to 2/3 of children with symptomatic convulsions in diseases with identified causes. Febrile seizures are a medical emergency in pediatrics.

7p vinatisu 29-08-2024 1 0   Download

Whitmore disease, alsocalled melioidosis, is an emerging infection in Vietnam after the heavy flood in 2020 with increasing case reports, mostly in adults but also in children. We report a child with parotid abscess, which is one of the common clinical manifestations in the paediatric population in Vietnam. He was previously healthy.

4p vinatisu 29-08-2024 3 1   Download

Multiple screening tools exist but the length of the examination and the false positive rate range from good to adequate. A screening tool was designed and tested in the emergency department using nurse responders without a scoring system.

5p vinatisu 29-08-2024 5 1   Download

A new emerged lethal disease that termed EMS (Early Mortality Syndrome) or AHPNS (Acute Hepatopancreatic Necrosis Syndrome) caused by Vibrio parahaemolyticus had been added to list of shrimp diseases during last recent years. However, there are no currently available methods to treat EMS.

9p nguyenvanhoangvnu 12-06-2017 51 2   Download

Plasmodium falciparum malaria remains a serious endemic disease in many parts of the world. It is estimated that 120 million cases occur worldwide each year, causing over one million deaths. The problem has been compounded by the emergence of strains of P. falciparum resistant to virtually all antimalarial agents. Resistance to chloroquine has now spread to almost all areas where malaria is endemic. Chloroquine-resistant strains are typically cross resistant to all drugs of relative chemical structure, and therefore the need for finding new molecules with novel modes of action is urgent.

4p uocvong04 24-09-2015 36 4   Download

The Nipah and Hendra viruses are highly pathogenic paramyxoviruses that recently emerged from flying foxes to cause serious disease outbreaks in humans and livestock in Australia, Malaysia, Singapore and Bangladesh. Their unique genetic constitution, high virulence and wide host range set them apart from other paramyxoviruses. These characteristics have led to their classification into the new genus Henpaviruswithin the family Para-myxoviridae and to their designation as Biosafety Level 4 pathogens. ...

10p tumor12 20-04-2013 32 1   Download

Dengue is a re-emerging viral disease, affecting approx. 100 million individ-uals annually. The monoclonal antibody mAb4E11 neutralizes the four serotypes of the dengue virus, but not other flaviviruses. Its epitope is included within the highly immunogenic domain 3 of the envelope glyco-protein E.

13p dell39 27-03-2013 35 3   Download

We briefly introduce the most common lysosomal storage disorder, Gau-cher disease, concisely describe the Food and Drug Administration approved strategies to ameliorate Gaucher disease, and then outline the emerging pharmacologic chaperone strategy that offers the promise to remedy this malady.

7p media19 04-03-2013 34 3   Download

Enzyme enhancement therapy is an emerging therapeutic approach that has the potential to treat many genetic diseases. Candidate diseases are those associated with a mutant protein that has difficulty folding and⁄or assembling into active oligomers in the endoplasmic reticulum.

11p media19 04-03-2013 38 2   Download

Heterozygous loss-of-function mutations at the glucosecerebrosidase locus have recently been shown to be a potent risk factor for Lewy body disease. Based on this observation, we have re-evaluated the likelihood that the dif-ferent PARK loci (defined using clinical criteria for disease) may be misleading attempts to find common pathways to pathogenesis.

7p vinaphone15 28-02-2013 49 3   Download

The last decade has seen clear links emerge between the genetic determi-nants and neuropathological hallmarks of parkinsonism and dementia, notably with the discovery of mutations ina-synuclein and tau. Following the description of mutations in LRRK2 linked to Parkinson’s disease, char-acterized by variable pathology including eithera-synuclein or tau deposi-tion, it has been suggested that LRRK2 functions as an upstream regulator of Parkinson’s disease pathogenesis.

10p vinaphone15 28-02-2013 29 3   Download

Rare, inherited mutations causing familial forms of Parkinson’s disease have provided insight into the molecular mechanisms that underlie the genetic and sporadic forms of this disease. Loss of protein function result-ing from autosomal-recessive mutations in PTEN-induced putative kinase 1 (PINK1), Parkin and DJ-1 has been linked to mitochondrial dysfunction, accumulation of abnormal and misfolded proteins, impaired protein clear-ance and oxidative stress.

9p vinaphone15 28-02-2013 39 3   Download

Tuberculosis (TB) continues to be a major cause of morbidity and mortal-ity worldwide. The increasing emergence and spread of drug-resistant TB poses a significant threat to disease control and calls for the urgent devel-opment of new drugs. The tryptophan biosynthetic pathway plays an important role in the survival of Mycobacterium tuberculosis.

11p vinaphone15 27-02-2013 48 2   Download

One of the emerging approaches for the treatment of Alzheimer’s disease aims at reducing toxic levels of Ab-species through the modulation of secretases, namely by inducing a-secretase or inhibiting b-secretase and⁄or c-secretase activities, or a combination of both.

11p viettel02 22-02-2013 31 3   Download

Protein kinases drive the cellular signal transduction networks that underlie the regulation of growth, survival and differentiation. To repair the deregu-lations of signaling cascades that are associated with numerous disease states, therapeutic strategies, based on controlling aberrant protein kinase activity, are emerging.

9p viettel02 20-02-2013 42 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Prospects for control of emerging infectious diseases with plasmid DNA vaccines...

9p thulanh27 13-12-2011 58 5   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Combination of lung ultrasound (a comet-tail sign) and N-terminal pro-brain natriuretic peptide in differentiating acute heart failure from chronic obstructive pulmonary disease and asthma as cause of acute dyspnea in prehospital emergency setting...

9p coxanh_8 05-11-2011 44 2   Download

Tuyển tập các báo cáo nghiên cứu về bệnh thú y được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành thú y đề tài: A Concept for a Decision Support System Based on Practical Experiences from a National Disease Emergency The Dutch Experience...

9p hoami_2511 21-10-2011 60 3   Download

Steven K Lundy, Sujata Sarkar, Laura A Tesmer and David A Fox Department of Internal Medicine, Division of Rheumatology and Rheumatic Diseases Core Center, University of Michigan Medical School, 4043 Biomedical Sciences Research Bldg., 109 Zina Pitcher Pl., Ann Arbor, MI 48109-2200, USA Corresponding author: David A Fox, dfox@umich.edu Published: 13 February 2007 This article is online at http://arthritis-research.com/content/9/1/202 © 2007 BioMed Central Ltd Arthritis Research & Therapy 2007, 9:202 (doi:10.

11p thulanh13 15-10-2011 59 1   Download