Enone synthesis
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An efficient synthetic route has been described for the alkylation of 1H -indole, 1H -benzimidazole, and 1H -benzotriazole. This approach features the alkylation of heteroaromatics through in situ generated enones from ketonic Mannich bases under metal-free conditions. A series of alkylated heteroaromatics have been synthesized via the K10 catalyzed alkylation reactions of these heteroaromatics with a variety of ketonic Mannich bases.
13p tudichquannguyet 29-11-2021 13 1 Download
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(bq) part 1 book "organic synthesis strategy and control" has contents: chemoselectivity, alternative strategies for enone synthesis, controlling the michael reaction, extended enolates; specific enol equivalents, electrophilic attack on alkenes,...and other contents.
443p bautroibinhyen20 06-03-2017 33 5 Download