Functional deterioration

Xem 1-20 trên 26 kết quả Functional deterioration
  • This study investigated the effect of transplantation of bone marrow mesenchymal stem cells (BM-MSCs) on functional deterioration and neuroinflammatory response in aged C57BL/6J mice. Mice were divided into 3 groups: Normal aged group, saline control group, and BM-MSCs treatment group.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells...

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  • We have developed an order level inventory system for deteriorating items with demand rate as a ramp type function of time. The finite production rate is proportional to the demand rate and the deterioration rate is independent of time. The unit production cost is inversely proportional to the demand rate.

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  • In this paper, we develop an inventory model for non-instantaneous deteriorating items under the consideration of the facts: deterioration rate can be controlled by using the preservation technology (PT) during deteriorating period, and holding cost and demand rate both are linear function of time, which was treated as constant in most of the deteriorating inventory models.

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  • This paper develops a finite time-horizon fuzzy multi-deteriorating inventory model with/without shortage, where the demand increases linearly with time. Here, the total profit is to be maximized under the limitation on investment. In this problem, total profit, total investment cost and the time-horizon are fuzzy in nature. The impreciseness in the above objective and constraint goals have been expressed by fuzzy linear/nonlinear membership functions and vagueness in time-horizon by different types of fuzzy numbers. Results are illustrated with numerical examples.

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  • This study proposes an EOQ inventory mathematical model for deteriorating items with exponentially decreasing demand. In the model, the shortages are allowed and partially backordered. The backlogging rate is variable and dependent on the waiting time for the next replenishment. Further, we show that the minimized objective cost function is jointly convex and derive the optimal solution. A numerical example is presented to illustrate the model and the sensitivity analysis is also studied.

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  • In this paper, an EOQ inventory model is depleted not only by time varying demand but also by Weibull distribution deterioration, in which the inventory is permitted to start with shortages and end without shortages. A theory is developed to obtain the optimal solution of the problem; it is then illustrated with the aid of several numerical examples.

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  • A third role of banks in the money market is to provide, in exchange for fees, commitments that help insure that investors in money market securities will be paid on a timely basis. One type of commitment is a backup line of credit to issuers of money market securities, which is typically dependent on the financial condition of the issuer and can be withdrawn if that condition deteriorates. Another type of commitment is a credit enhancement—generally in the form of a letter of credit—that guarantees that the bank will redeem a security upon...

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  • In 1871, over 30 years before Alois Alzheimer published his seminal cases, James Crichton - Browne may have been among the fi rst physicians to remark upon the relationship between “ brain wasting ” and “ premature dotage ” in a letter to Charles Darwin (Snyder & Pearn, 2007 ). Age - related mental deterioration as an entity had been recognized virtually for recorded history (Boller et al., 2007 ; Mandell & Albert, 1990 ).

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  • The effect of both types of discounts in optimising the profit is examined through numerical illustrations. Sensitivity analysis is also appended to find out the effect of various system parameters. From this study it is observed that it will be more advantageous for management to offer pre deterioration discount in enticing the profit.

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  • The inventory-level demand reflects a real market demand for product whose sales is enhanced by stock on display. We study a case base examples to gain some quantitative insight into the proposed model and we perform sensitivity analysis to draw some managerial implications.

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  • In this paper, an inventory model with general ramp-type demand rate, partial backlogging of unsatisfied demand and time-varying holding cost is considered; where the “Time-varying holding cost” means that the holding cost is a function of time, i.e. it is time dependent. The model is studied under the following different replenishment policies: (1) starting with no shortages (2) starting with shortages.

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  • The present paper deals with an economic order quantity (EOQ) model of an inventory problem with alternating demand rate: (i) For a certain period, the demand rate is a non linear function of the instantaneous inventory level. (ii) For the rest of the cycle, the demand rate is time dependent. The time at which demand rate changes, may be deterministic or uncertain.

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  • The concept of forest sustainability dates from centuries ago, although the understanding of sustainable forest management (SFM) as an instrument that harmonizes ecological and socio-economic concerns is relatively new. The change in perspective occurred at the beginning of the 1990s in response to an increased awareness of the deterioration of the environment, in particular of the alarming loss of forest resources. The main and most striking cause of this deterioration is the deforestation occurring in some areas of the world.

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  • CHAPTER 25 LUBRICATION A. R. Lansdown, M.Sc., Ph.D. Director, Swansea Tribology Centre University College of Swansea Swansea, United Kingdom 25.1 FUNCTIONS AND TYPES OF LUBRICANT / 25.1 25.2 SELECTION OF LUBRICANT TYPE / 25.2 25.3 LIQUID LUBRICANTS: PRINCIPLES AND REQUIREMENTS / 25.3 25.4 LUBRICANT VISCOSITY / 25.6 25.5 BOUNDARY LUBRICATION / 25.9 25.6 DETERIORATION PROBLEMS /25.12 25.7 SELECTING THE OIL TYPE /25.14 25.8 LUBRICATING GREASES /25.17 25.9 SOLID LUBRICANTS / 25.22 25.10 GAS LUBRICATION / 25.26 25.11 LUBRICANT FEED SYSTEMS / 25.26 25.12 LUBRICANT STORAGE / 25.

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  • Background: Chronic kidney disease (CKD) is characterized by an irreversible deterioration of renal function that gradually progresses to end-stage renal disease (ESRD). CKD has emerged as a serious public health problem.

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  • Skeletal muscle contractions power human body movements and are essential for maintaining stability. Skeletal muscle tissue accounts for almost half of the human body mass and, in addition to its power-generating role, is a crucial factor in maintaining homeostasis. Given its central role in human mobility and metabolic function, any deterioration in the contractile, material, and metabolic properties of skeletal muscle has an extremely important effect on human health.

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  • Senescence is a biological process that causes a progressive deterioration of structure and function of all organs chronologically. Recent studies have revealed the detailed molecular mechanisms of senescence using cell culture system and experimental organisms. It is thought that senescence is a potential cause for the development of various age-related disorders such as cancer, cardiovascular and neurodegenerative disorders.

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  • 3 functions: 1/ Medium of Exchange—promotes economic efficiency by minimizing the time spent in exchanging goods and services Must be easily standardized Must be widely accepted Must be divisible Must be easy to carry Must not deteriorate quickly 2/ Unit of Account—used to measure value in the economy: we measure the value of goods & services in terms of money. 3/ Store of Value— power - used to save purchasing power; most liquid of all assets (that why we want to keep money) but loses value during inflation ...

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  • Agitation (dễ cáu gắt) is an unpleasant state of extreme arousal, increased tension, and irritability anxiety (lo lắng) Fear or apprehension or dread of impending danger and accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus.

    pdf7p truongthiuyen1 09-06-2011 54 4   Download



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