Macroautophagy
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Macroautophagy is a vital process in the cardiac myocyte: it plays a pro-tective role in the response to ischemic injury, and chronic perturbation is causative in heart disease. Recent findings evidence a link between the apoptotic and autophagic pathways through the interaction of the anti-apoptotic proteins Bcl-2 and Bcl-XLwith Beclin 1.
14p 
galaxyss3
19-03-2013
40
3
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Macroautophagy (hereafter referred to as autophagy) is a tightly regulated lysosome-dependent catabolic pathway. During this process, cytosolic con-stituents are sequestered into autophagosomes, which subsequently fuse with lysosomes to become autolysosomes, where their contents are degraded.
13p viettel02
20-02-2013
45
3
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