Mechanistic overview

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  • It is my great honor and pleasure to introduce this comprehensive book to readers who are interested in carbohydrates. This book contains 23 excellent chapters written by experts from the fields of chemistry, glycobiology, microbiology, immunology, botany, zoology, as well as biotechnology. According to the topics, methods and targets, the 23 chapters are further divided into five independent sections. In addition to the basic research, this book also offers much in the way of experiences, tools, and technologies for readers who are interested in different fields of Glycobiology.

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  • The hypothalamic decapeptide gonadotropin-releasing hormone (GnRH) is well known for its role in the control of pituitary gonadotropin secretion, but the hormone and receptor are also expressed in extrapituitary tissues and tumor cells, including epithelial ovarian cancers.

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  • Acyl-CoA dehydrogenases constitute a family of flavopro-teins that catalyze the a,b-dehydrogenation of fatty acid acyl-CoA conjugates. While they differ widely in their spe-cificity, they share the same basic chemical mechanism ofa,b-dehydrogenation. Medium chain acyl-CoAdehydro-genase is probably the best-studiedmember of the class and serves as a model for the study of catalytic mechanisms.

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  • Mass Spectrometry of Carbohydrates Derivatized with Biotinamidocaproyl Hydrazide 55 Stephanie Bank and Petra Kapková Investigation of Carbohydrates and Their Derivatives as Crystallization Modifiers 81 Josef Jampílek and Jiří Dohnal Glycosidases – A Mechanistic Overview 117 Natércia

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