Xem 1-3 trên 3 kết quả Microheterogeneity
  • Prolactin is a polypeptide hormone that is synthesized in and secreted from the lactotrophs of the anterior pituitary gland. We are now aware that synthesis and secretion of prolactin is not restricted to the anterior lobe of the pituitary gland, but other organs and individual cells can also produce it. This book provides the headlines to follow a course of cumulated knowledge on prolactin research during the last two-three decades and it may also help us understand some of the concerns that we face today....

    pdf244p phoebe75 19-02-2013 16 3   Download

  • The catalytic module ofHypocrea jecorina(previously Trichoderma reesei) Cel7B was homologously expressed by transformation of strain QM9414. Post-translational modi-fications in purified Cel7B preparations were analysed by enzymatic digestions, high performance chromatography, mass spectrometry and site-directed mutagenesis. Of the five potential sites found in the wild-type enzyme, only Asn56 and Asn182 were found to be N-glycosylated.

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  • There are different glycosylated proteins in snake venoms, but no glycosylated representatives of a large family of three-fingered toxins have previously been detected. A new glycoprotein was isolated from the venom of the Thai cobra Naja kaouthia. MALDI MS of the glycoprotein contained an array of peaks in the range from 8900 to 9400 Da indicating its microheterogeneity. Carbohy-drate analysis showed the presence of mannose, galactose, N-acetylglucosamine, fucose and neuraminic acid.

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