Narcotic analgesics

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  • Danh pháp : + Hạ sốt - Giảm đau - Chống viêm:HS-GĐ-CV + Thuốc chống viêm phi steroid ( CVPS / NSAIDs / AINS ) ( ≠ SAIDs / AIS ).? + Thuốc trị thấp khớp, kháng viêm và giảm đau, hạ sốt. + Thuốc giảm đau khụng gây ngủ + NSAIDs = Nonsteroidal anti-inflammatory drugs + AINS = Anti-inflammatoires non-steroidiens ( ≠ AIS ). + Antirheumatic, anti-inflammatory, analgesics and antipyretics. + Nonnarcotic analgesics ( ≠ narcotic analgesics ).

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  • Introduction: Pentazocine ( Fig. 5.1) is a non-narcotic analgesic, but shows mild dependence; there are many cases of pentazocine abuse especially for medical and co-medical workers. The drug is being regulated as a subclass compound of narcotics (DEA class: IV). Pentazocine in both antemortem and postmortem specimens is being analyzed by GC [1–4], HPLC [5–7] and GC/MS [8]. In this chapter, a simple method for GC/MS analysis of pentazocine in human whole blood and urine is presented. ⊡ Figure 5.1 Structures of pentazocine and dextromethorphan (IS).

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  • Introduction: There are a number of compounds, such as morphine and codeine, which are classified into the opium alkaloids (opiates). They are being used as ethical drugs of narcotic analgesics and antitussives; 1 % powder of codeine or dihydrocodeine is commonly included in over-the-counter drugs of antitussives. Figure 3.1 shows metabolic pathways of morphine, heroin and codeine. Since morphine and codeine are finally excreted into urine in the conjugated forms with glucuronic acid [1–3], it is necessary to hydrolyze the conjugated forms of these compounds before GC/MS analysis.

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  • Pharmacology has undergone major intellectual changes in the recent years and has become increasingly important to all medical, dental and other health professionals. The graduate students of dentistry may have to handle medical emergency during various dental procedures on the dental chair. Besides this, dentists have to look into various drug associated interactions. The broad goal of teaching pharmacology to undergraduate students is to inculcate rational and scientific basis of therapeutics keeping in view the dental curriculum and profession.

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  • Complications Following Hematopoietic Cell Transplant Early Direct Chemoradiotoxicities The transplant preparative regimens commonly used cause a spectrum of acute toxicities that vary according to the specific regimen but frequently result in nausea, vomiting, and mild skin erythema (Fig. 108-1). Regimens that include high-dose cyclophosphamide can result in hemorrhagic cystitis, which can usually be prevented by bladder irrigation or with the sulfhydryl compound mercaptoethanesulfonate (MESNA); rarely, acute hemorrhagic carditis is seen.

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  • The seventh edition of Introductory Clinical Pharmacology reflects the ever-changing science of pharmacology and the nurse’s responsibilities in administering pharmacologic agents. All information has been updated and revised according to the latest available information to prepare nurses to meet the challenges of safely administering medications. The text prepares the nurse to meet the challenges of the 21st century by promoting critical thinking and problem solving when administering medications....

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