Neural stem cell

The process of neural stem cell (NSC) differentiation into neurons is crucial for the development of potential cell-centered treatments for central nervous system disorders. However, predicting, identifying, and anticipating this differentiation is complex. In this study, we propose the implementation of a convolutional neural network model for the predictable recognition of NSC fate, utilizing single-cell brightfield images.

7p viengfa 28-10-2024 2 2   Download

Glioma stem cells (GSCs) are a subpopulation of stem-like cells that contribute to glioblastoma (GBM) aggressiveness, recurrence, and resistance to radiation and chemotherapy. Therapeutically targeting the GSC population may improve patient survival, but unique vulnerabilities need to be identified.

25p vimichaelfaraday 25-03-2022 24 1   Download

We recently reported that intermittent hypoxia facilitated the proliferation of neural stem⁄progenitor cells (NPCs) in the subventricule zone and hip-pocampusin vivo. Here, we demonstrate that hypoxia promoted the prolif-eration of NPCsin vitro and that hypoxia-inducible factor (HIF)-1a, which is one of the key molecules in the response to hypoxia, was critical in this process.

11p media19 06-03-2013 38 1   Download

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài :Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model

11p dauphong3 03-01-2012 72 4   Download

Neural induction is a complex process and the detailed mechanism of FGF-induced neurogenesis remains unclear. Methods: By using a serum-free neural induction method, we showed that FGF1 dose-dependently promoted the induction of Sox1/N-cadherin/nestin triple positive cells, which represent primitive neuroblasts, from mouse embryonic stem (ES) cells. Results: We demonstrated that FGF1, FGF2, and FGF4, but not FGF8b, enhanced this neurogenesis. Especially, FGFenhanced neurogenesis is not mediated through the rescue of the apoptosis or the enhancement of the proliferation of Sox1+ cells.

11p toshiba23 18-11-2011 57 3   Download

As the origin of a life-and-death signal detected from systemic arterial pressure, which sequentially increases (pro-life) and decreases (pro-death) to reflect progressive dysfunction of central cardiovascular regulation during the advancement towards brain stem death in critically ill patients, the rostral ventrolateral medulla (RVLM) is a suitable neural substrate for mechanistic delineation of this fatal phenomenon.

9p toshiba23 18-11-2011 46 2   Download

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells...

6p thulanh8 06-10-2011 51 4   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Functional recovery and neural differentiation after transplantation of allogenic adipose-derived stem cells in a canine model of acute spinal cord injury

12p hoami_238 19-09-2011 42 2   Download

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Compound developmental eye disorders following inactivation of TGF signaling in neural-crest stem cells...

16p toshiba3 07-09-2011 43 5   Download