Physiology of behavior

Calpains are intracellular Ca 2+ -regulated cysteine pro-teases which mediate regulatory cleavage of specific substrates. They cover a broad range of physiological functions including proteolysis of molecules involved in cytoskeletal organization, the cell cycle, signal trans-duction, apoptosis, and protein renewal during growth and tissue regeneration. Originally found in mamma-lian skeletal muscle then in numerous organisms inclu-ding protists and plants, their expression is ubiquitous [1,2].

2p inspiron33 25-03-2013 41 4   Download

The hypothalamic neuropeptides modulate physiological activity via G pro-tein-coupled receptors (GPCRs). Galanin-like peptide (GALP) is a 60 amino acid neuropeptide that was originally isolated from porcine hypo-thalamus using a binding assay for galanin receptors, which belong to the GPCR family.

8p viettel02 19-02-2013 39 2   Download