Releasing hormone

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  • Hormones release of STH (and also other peptide hormones including insulin, glucagon, and gastrin). PRH: prolactin-RH remains to be characterized or established. Both TRH and vasoactive intestinal peptide (VIP) are implicated. PRIH inhibits the release of prolactin and could be identical with dopamine. Hypothalamic releasing hormones are mostly administered (parenterally) for diagnostic reasons to test AH function. Therapeutic control of AH cells. GnRH is used in hypothalamic infertility in women to stimulate FSH and LH secretion and to induce ovulation.

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  • Gonadotropin-releasing hormone antagonists (GnRH-nt) available for clinical use are GnRH molecules with amino acid modifications in positions 1, 2, 3, 6, and 10. They are not associated with the histaminic-release effects of previous compounds (1). These compounds immediately block GnRH receptor in a competitive fashion (2). They decrease the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion within a period of eight hours. Inhibition of LH secretion is more important than FSH.

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  • Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter

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  • The hypothalamic decapeptide gonadotropin-releasing hormone (GnRH) is well known for its role in the control of pituitary gonadotropin secretion, but the hormone and receptor are also expressed in extrapituitary tissues and tumor cells, including epithelial ovarian cancers.

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  • Protein kinase Ce (PKCe) is activated by thyrotropin-releasing hormone (TRH), a regulator of pituitary function in rat pituitary GH4C1 cells. We analyzed the downstream mechanism after PKCe activation. Exposure of GH4C1 cells to TRH or a phorbol ester increased the phosphorylation of three p52 proteins (p52a, p52b and p52c) and decreased the phosphoryla-tion of destrin and cofilin.

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  • Thyrotropin-releasing hormone receptor (TRHR) has already been cloned in mammals where thyrotropin-releas-inghormone (TRH) isknowntoactasapowerful stimulator of thyroid-stimulating hormone (TSH) secretion. The TRH receptor of amphibians has not yet been characterized, although TRH is specifically important in the adaptation of skin color to environmental changes via the secretion of a-melanocyte-stimulating hormone (a-MSH).

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  • Previous biochemical studies have indicated that the membrane-bound thyrotropin-releasing hormone (TRH)-degrading enzyme (TRH-DE) from brain and liver and the serum TRH-DE are derived from the same gene. These studies also suggested that the serum enzyme is of liver origin. The present study was undertaken to verify these hypotheses. In different species, a close relationship between the activities of the serum enzyme and the particulate liver enzyme was noticed.

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  • Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Induction of castration by immunization of male dogs with recombinant gonadotropin-releasing hormone (GnRH)-canine distemper virus (CDV) T helper cell epitope p35

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  • As the key regulator of reproduction, gonadotropin-releasing hormone (GnRH) is released by neurons in the hypothalamus, and transported via the hypothalamo-hypophyseal portal circulation to the anterior pituitary to trigger gonadotropin release for gonadal steroidogenesis and gametogene-sis.

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  • Gonadotropin-releasing hormone (GnRH) has historically been known as a pituitary hormone; however, in the past few years, interest has been raised in locally produced, extrapituitary GnRH. GnRH receptor (GnRHR) was found to be expressed in normal human reproductive tissues (e.g. breast, endometrium, ovary, and prostate) and tumors derived from these tissues.

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  • During the last two decades, evidence of increasing trends of several endocrine-related disorders has been strengthened. These disorders often come with lack of uniform diagnosis and/ or even unclear endocrine disruption. The later is mainly due to abnormal classical changes in the blood- released hormone to its targeted organ, abnormal communication between cells within a tissue or organ (paracrine), within the same cell (intracrine) or signals which act on the same cell (autocrine).

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  • The  Port  Authority  of  New  York  and  New  Jersey  (the  “Port  Authority”)  is  a  complex  organization,  comprised  of  billions  of  dollars  of  vital  infrastructure  and  transportation  operations as well as significant real estate holdings.  Navigant Consulting, Inc.

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  • It is well established that the intracellular second messenger cADP-ribose (cADPR) activates Ca 2+ release from the sarcoplasmic reticulum through ryanodine receptors. CD38 is a multifunctional enzyme involved in the for-mation of cADPR in mammals.

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  • As one class of the most important steroid hormones, glucocorticoids have long been recognised and their therapeutic benefits have been widely used in clinical treatment, especially in anti-inflammation cases.

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  • Inhibin là hormone glycoprotein của tuyến sinh dục, nó ức chế có chọn lọc sự xuất tiết của FSH ở cả đực, cái của loài có vú. FSH tuyến yên là cần thiết cho sự phát triển? và duy trì nang trứng ở các loài động vật rụng một hay rụng nhiều trứng.

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  • TRH là viết tắt của hormon giải phóng thyrotropin (tảiotropin releasing hormone). Cấu trúc hoá học của TRH dã được Schally và Guilemin xác định (năm 1969 và đạt giải thưởng Nobel 1977) là một peptid ngắn chỉ 3 amino acid là pyroglutamyl-histidyl-proline-NH2. TRH có chức năng tham gia vào quá trình tổng hợp và bài tiết TSH (kích giáp trạng tố). TRH có chức năng vừa như một hormon giải phóng, vừa như một hormon kích thích. ...

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  • Chương 9. THUỐC TÁC ĐỘNG LÊN HỆ SINH DỤC VÀ TIẾT NIỆU 9.1. Nội tiết tố sinh dục Các họat động trong chu kỳ sinh dục được điều khiển bởi hệ thần kinh và nội tiết theo cơ chế phản hồi âm tính (negative feedback) hay điều khiển ngược.

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  • 1.1. Vùng dưới đồi Trung khu sinh dục vùng dưới đồi nằm trong nền trung não, phía trên giao thoa thị giác, gồm một nhóm nhân thần kinh giàu mạch máu, có khả năng chế tiết hormon. Nhân trên thị chế tiết vasopressin, nhân bên thất chế tiết oxytocin, các chất này được các sợi thần kinh dẫn xuống thùy sau tuyến yên. Củ xám, nhân bụng giữa, nhân lưng giữa và nhân cung tiết ra các hormon giải phóng.

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  • In neurointensive patients with acute lung injury, achieving the goal of lung protection without threatening cerebral perfusion is very difficult. In patients with more refractory raised intracranial pressure, the optimal balance between brain and lung may not be well established. Multiple strategies are used to recruit atelectatic alveoli and improve oxygenation. Among them incremental levels of PEEP and high intermittent tidal volumes should require extend brain physiological monitoring.

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  • The new toolkit focuses on relapse prevention, risks of secondhand smoke exposure and the health benefits of quitting smoking for mother and infant. It also emphasizes the potential and underlying issues related to relapse including postpartum depression, stress and miscarriage. An appendix for counselors to use as a reference tool during counseling sessions is also included in the toolkit.

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