Role of glial cells

Chronic osteoarthritic pain is not well understood in terms of its pathophysiological mechanism. Activated glial cells are thought to play a role in the maintenance of chronic pain. T98G glioblastoma cell line was previously observed to release higher amounts of interleukin-6 (IL-6) when treated with cerebrospinal fluid (CSF) from patients with another chronic pain condition, post-herpetic neuralgia.

7p vizhangzhidong 29-12-2021 7 0   Download

Histone deacetylases (HDACs) play important roles in glial cell development and in disease states within multiple regions of the central nervous system. However, little is known about HDAC expression or function within the optic nerve.

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Little is known about the role of glial host cells in brain tumours. However, supporting stromal cells have been shown to foster tumour growth in other cancers. This cell population was subsequently characterised using gene expression analyses and immunocytochemistry. Furthermore, sphere formation was assessed in vitro and their glioma growth-promoting ability was examined in vivo. Finally, the expression of TAG related markers was validated in human GBMs.

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Gliomas account for the majority of primary human brain tumors and remain a challenging neoplasm for cure due to limited therapeutic options. Cell adhesion molecules play pivotal roles in the growth and progression of glial tumors.

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Evidence indicates that reactive astrocytes play an important role in neurological functional amelioration after stroke. Bone marrow stromal cell (BMSC) transplantation-promoted astrocyte-derived neurotrophic factors’ expressions resulted in decreasing the number of apoptotic neurons and improving neurogenesis and angiogenesis in the ischemic boundary zone.

10p sony2711 28-01-2019 16 0   Download

Using an NSOM for confocal microscopy actin in the brain, nanopositioning, role of glial cells and actin in the brain,... As the main contents of the document "Role of precision motion control in brain cell research". Invite you to consult

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Glial cell line-derived neurotrophic factor family ligands act through the receptor tyrosine kinase Ret, which plays important roles during embryonic development for cell differentiation, survival, and migration. Ret signaling is markedly affected by compartmentalization of receptor complexes into membrane subdomains.

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The process likely begins with the development of defects in the supply of cholesterol and fats to neurons, progressing to extensive oxidative damage, mitochondrial defects, and a shift of metabolism towards utilizing sources other than glucose and minimizing mito- chondrial involvement. In the end stage, neurons can no longer transmit signals effectively, and apoptosis is the best option to avoid damaging neighboring cells. A crucial role is played by astrocytes, the glial cells that supply cholesterol and fats to neurons.

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Tham khảo sách 'novel insights on chronic kidney disease, acute kidney injury and polycystic kidney disease', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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Arterial CO2 tension is a powerful modulator of cerebral vascular calibre, CBF and ICP (12-15.) While the mechanisms are incompletely understood, CO2 relaxes pial arterioles by interactions between the endothelium, vascular smooth muscle, pericytes, adjacent neurons and glial cells. Studies supported that cerebral vessels are sensitive to changes in extracellular pH, rather than a direct response to CO2 or bicarbonate. In the limits of physiological PaCO2, 20-60 mmHg, the relationship between PaCO2 and CBF is linear.

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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells

12p panasonic09 12-01-2012 37 3   Download