Specific drug groups

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  • Photodynamic therapy (PDT) applications enable light-controlled activation of drug candidates instead of their constitutive activities to prevent undesired side effects associated with their constant activities. A specific wavelength of light is utilized to enable electron mobility in the chemical structure, which results in differential activities that may alter cell viability and cellular functions. Canonical photodynamic therapy applications mostly focus on cytotoxicity-based antimicrobial and anticancer properties of the PDT agents.

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  • Biomedical literature concerns a wide range of concepts, requiring controlled vocabularies to maintain a consistent terminology across different research groups. However, as new concepts are introduced, biomedical literature is prone to ambiguity, specifically in fields that are advancing more rapidly, for example, drug design and development.

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  • In past, numerous quantitative structure-activity relationship (QSAR) based models have been developed for predicting anticancer activity for a specific class of molecules against different cancer drug targets. In contrast, limited attempt have been made to predict the anticancer activity of a diverse class of chemicals against a wide variety of cancer cell lines.

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  • Breast cancer risk, development, and treatment are influenced by genetic variation in certain genes, namely those involved in cell proliferation, tumor suppression, and drug metabolism. In turn, the relevance of the aforementioned genetic variation to cancer depends on the ethnic group in question, highlighting the need for population-specific association studies.

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  • The study was conducted at TVCC, Nagpur at which a total of 219 dogs showed signs of azotemia with BUN level above 25 mg/dL and Serum. Creatinine level of more than 2 mg/dL. Of these dogs, 30 dogs were selected at random and divided into three groups comprising of 10 dogs each. Urinalysis was carried out at 0, 18 and 30 days interval along with urine culture and Antibiotic Sensitivity tests which were carried out initially to know the specific drug to be used for the treatment. Ultrasonography was conducted in all cases to record the different findings in dogs suffering from renal failure.

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  • A total 18 dogs maintained at different places were screened and included in the study. All the dogs were put through preliminary screening for the presence of ascites and were subjected to thorough clinical examination including detailed physical and clinical investigation with special reference to haemato-biochemical estimation, ultrasonography and radiography. The dogs found positive were subjected to therapeutic study and were further divided into three groups, namely G II, G IIIand G IVcomprising of 6 animals in each group irrespective of their sex, breed and age. Another group i.e.

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  • To describe the utilisation of antibiotics in children and adolescents across 5 European countries based on the same drug utilisation measures and age groups. Special attention was given to age-group-specific distributions of antibiotic subgroups, since comparison in this regard between countries is lacking so far.

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  • (bq) part 2 book "prescribing at a glance" presentation of content: logistics of prescribing (how to write a drug prescription, communicating with patients about medicines, therapeutic drug monitoring, avoiding drug interactions,...), specific drug groups (using drugs for the respiratory system, using drugs for the neurological system i, using drugs for infection, an approach to common prescribing requests,...).

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  • This revision of the Global Strategy for Asthma Management and Prevention again provides a unified text as a source document. Each chapter contains separate sections containing details and management advice for specific age categories where these are considered relevant. These age groups include children 5 years and younger (sometimes called preschool age), children older than 5 years, adolescents, adults, and the elderly.

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  • After program outcomes are defined in general terms, the next step is to translate the statements into specific indicators that will be measured. For each outcome, the working group needs to identify one or more outcome indicators that could be measured to track progress toward the outcomes. Key criteria are the feasibility and cost of measurement. Outcome indicators should almost always begin with words such as “The number of . . .” or “The percent of . . .” Exhibit 8 illustrates the relationship between a program’s mission/objectives, outcomes, and outcome indicators.

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  • After researching literature on addiction and film, I chose the films for the study and viewed each one many times, specifically looking for socioeconomic representations of characters, treatment of different races, sexes, and sexual preferences, methods of production as they relate to addicted characters and drug usage, and the depiction of treatment/ self-help groups. I then outlined the narrative of each film and compared the uses and meanings brought to addicts, addiction, and substances. I found that these movies construct a fairly unified image of treatment.

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  • Many protein substrates of caspases are cleaved at noncanonical sites in comparison to the recognition motifs reported for the three caspase sub-groups. To provide insight into the specificity and aid in the design of drugs to control cell death, crystal structures of caspase-7 were determined in complexes with six peptide analogs (Ac-DMQD-Cho, Ac-DQMD-Cho, Ac-DNLD-Cho, Ac-IEPD-Cho, Ac-ESMD-Cho, Ac-WEHD-Cho) that span the major recognition motifs of the three subgroups.

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  • Women constitute a special group within prisons because of their sex. Although the characteristics and corresponding needs of women prisoners can vary considerably between countries, several factors are common to most. These include many mental disorders, a high level of drug or alcohol dependence, many women experiencing sexual and physical abuse and violence before or in prison, the neglect of gender-specific health care needs and additional issues related to the women’s responsibility for children and families.

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  • A major element of personalized medicine involves the identification of therapeutic regimes that are safe and effective for specific patients. This contrasts the “one-size- fits-all” well-known concept of “blockbuster” drugs, which are considered safe and effective for the entire population. The concept of targeted patient groups falls in- between these two extremes with the identification of therapeutic regimes targeted to be safe and effective for specific patient groups with similar characteristics [1].

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  • Introduction: The aconite plants contain Aconitum alkaloids (AAs) and other minor components, such as chasmanine, kobusine and higenamine. AAs consist of aconitines, benzoylaconines and aconines as shown in Figure 1.1. The most toxic group is the aconitines, including aconitine, mesaconitine, hypaconitine, and jesaconitine; this group is one of the most poisonous compounds being contained in the plant kingdom. Even nowadays, aconite poisoning cases take place occasionally. These may be due to accidental, suicidal or homicidal ingestion of the plant itself or its extracts.

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