Support and protect

This paper describes the aims and achievements of these projects and, based on insights and experiences from these projects, provides some recommendations for future policy support regarding maintaining competences in nuclear industry and research.

7p christabelhuynh 29-05-2020 7 1   Download

Escherichia colifatty acid cyclopropane synthase (CFAS) was overproduced and purified as a His6 -tagged protein. This recombinant enzyme is as active as the native enzyme with aKmof 90lMforS-AdoMet and a specific activity of 5·10 )2 lmolÆmin )1 Æmg )1 . The enzyme is devoid of organic or metal cofactors and is unable to catalyze the wash-out of themethyl protons ofS-AdoMet to the solvent, data that do not support the ylidemechanism. Inactivationof the enzyme by 5,5¢-dithiobis-(2-nitrobenzoic acid) (DTNB), a pseudo first-order process with a rate constant of 1.

10p awards 05-04-2013 33 2   Download

Substantial levels of trehalose accumulate in bacteria, fungi, and inverte-brates, where it serves as a storage carbohydrate or as a protectant against environmental stresses. In higher plants, trehalose is detected at fairly low levels; therefore, a regulatory or signaling function has been proposed for this molecule.

10p galaxyss3 21-03-2013 22 3   Download

An emerging body of evidence supports a key role for the endocannabinoid system in numerous physiological and pathological mechanisms of the cen-tral nervous system. In the recent past, many experimental studies have examined the putative protective or toxic effects of drugs interacting with cannabinoid receptors or have measured the brain levels of endocannabi-noids inin vitro and in vivo models of cerebral ischemia.

11p vinaphone15 27-02-2013 40 3   Download