Suppressor genes

Xem 1-20 trên 40 kết quả Suppressor genes
  • Tumor suppressor genes (TSGs) and their signaling networks are fast growing areas in current biomedical science. These groups of genes, which are not limited to tumor suppression, play critical roles in many cellular activities. This book, "Future Aspects of Tumor Suppressor Genes", contains some fascinating fields, from basic to translational researches, in recent TSG studies. For example, several TSG signaling pathways are addressed in this book, and both mouse and Drosophila models used for the exploration of these genes are described based on the experimental evidence....

    pdf230p haiduong_1 15-04-2013 16 2   Download

  • Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer

    pdf11p dauphong4 03-01-2012 17 4   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Period-2: a tumor suppressor gene in breast cancer...

    pdf9p thulanh23 21-11-2011 20 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Retraction: The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma

    pdf1p toshiba22 21-11-2011 28 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties

    pdf10p toshiba22 21-11-2011 25 2   Download

  • Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Mutations of p53 Tumor Suppressor Gene in Spontaneous Canine Mammary Tumors

    pdf5p hoami_266 15-09-2011 28 1   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis...

    pdf7p thulanh12 13-10-2011 20 1   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Isolation of suppressor genes that restore retrovirus susceptibility to a virus-resistant cell line

    pdf10p toshiba16 27-10-2011 31 1   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing...

    pdf14p thulanh22 20-11-2011 19 1   Download

  • Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated. Insights have also been gained into the molecular mechanisms underlying carcinogenesis by chemical, physical, and biological agents and into inherited susceptibility to cancer. Accordingly, Part I of the book presents many of the molecules and mechanisms generally important in human cancers.

    pdf529p tom_123 15-11-2012 36 16   Download

  • Another local approach uses adenoviral-mediated expression of the tumor suppressor p53, which is mutated in a wide variety of cancers. This strategy has shown complete and partial responses in squamous cell carcinoma of the head and neck, esophageal cancer, and non-small cell lung cancer after direct intratumoral injection of the vector. Response rates (~15%) are comparable to those of other single agents.

    pdf5p konheokonmummim 03-12-2010 43 4   Download

  • HIC1(hypermethylated in cancer) is a tumour suppressor gene located in 17p13.3, a region frequently hypermethylated or deleted in many types of prevalent human tumour.HIC1is also a candidate for a contiguous-gene syndrome, the Miller–Dieker syndrome, a severe form of lissencephaly accompanied by developmental anomalies.

    pdf12p inspiron33 25-03-2013 11 2   Download

  • (BQ) Part 2 book "High-Yield cell and molecular biology - Cell and molecular biology" presents the following contents: Proto-Oncogenes, oncogenes and tumor-suppressor genes, the cell cycle, molecular biology of cancer, cell biology of the immune system, cell biology of the immune system, molecular biology techniques, identification of human disease genes, gene therapy.

    pdf94p thangnamvoiva3 28-06-2016 20 1   Download

  • Nội dung Ung thưcó phải bệnh di truyền? Các dạng biểu hiện của bệnh ung thư Ung thư và sự điều khiển chu trình tế bào Khái niệm về các gen gây KHốI U (oncogene) Khái niệm về các gen ức chế khối u (tumor suppressor genes) Các cơ chế di truyền liên quan đến sự phát sinh ung thư

    pdf5p poseidon09 10-08-2011 112 47   Download

  • In addition, although more rare, some patients might not present until weeks, if not longer, after their infarction with symptoms that prompt the discovery of a chronic PI- VSD. Early PI-VSDs tend to be catastrophic and typically result in early death.

    pdf344p wawawawawa 27-07-2012 77 6   Download

  • This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence.

    pdf496p phoebe75 19-02-2013 27 5   Download

  • General Classes of Cancer Genes There are two major classes of cancer genes. The first class comprises genes that directly affect cell growth either positively (oncogenes) or negatively (tumor-suppressor genes). These genes exert their effects on tumor growth through their ability to control cell division (cell birth) or cell death (apoptosis). Oncogenes are tightly regulated in normal cells. In cancer cells, oncogenes acquire mutations that relieve this control and lead to increased activity of the gene product.

    pdf5p konheokonmummim 03-12-2010 48 4   Download

  • Familial adenomatous polyposis (FAP) is a dominantly inherited colon cancer syndrome due to germline mutations in the adenomatous polyposis coli (APC) tumor-suppressor gene on chromosome 5. Patients with this syndrome develop hundreds to thousands of adenomas in the colon. Each of these adenomas has lost the normal remaining allele of APC but has not yet accumulated the required additional mutations to generate fully malignant cells (Fig. 79-2).

    pdf5p konheokonmummim 03-12-2010 34 4   Download

  • While most autosomal dominant inherited cancer syndromes are due to mutations in tumor-suppressor genes (Table 79-1), there are a few interesting exceptions. Multiple endocrine neoplasia type II, a dominant disorder characterized by pituitary adenomas, medullary carcinoma of the thyroid, and (in some pedigrees) pheochromocytoma, is due to gain-of-function mutations in the protooncogene RET on chromosome 10. Similarly, gain-of-function mutations in the tyrosine kinase domain of the MET oncogene lead to hereditary papillary renal carcinoma.

    pdf5p konheokonmummim 03-12-2010 39 4   Download

  • While researching this book, I came across a letter in the journal Nature asking for caution in the current trend for the use of humorous nomenclature for newly discovered genes1, the author referring to the tumour suppressor gene Pokemon, which I have briefly described in Chapter 4.

    pdf349p hyperion75 18-01-2013 24 4   Download


Đồng bộ tài khoản