The c subset

Nuclear receptors (NRs) are ligand-regulated, DNA-binding transcription factors that function in the chromatin environment of the nucleus to alter the expression of subsets of hormone-responsive genes. It is clear that chromatin, rather than being a passive player, has a profound effect on both transcriptional repression and activation mediated by NRs.

9p research12 01-06-2013 32 2   Download

Thec-secretase complex mediates the final proteolytic event in Alzheimer’s disease amyloid-bbiogenesis. This membrane complex of presenilin, ante-rior pharynx defective, nicastrin, and presenilin enhancer-2 cleaves the C-terminal 99-amino acid fragment of the amyloid precursor protein intra-membranously atc-sites to form C-terminally heterogeneous amyloid-b and cleaves at ane-site to release the intracellular domain or e-C-terminal fragment.

14p fptmusic 12-04-2013 39 5   Download

Nociceptors are specialized nerve fibers that transmit noxious pain stimuli to the dorsal horn of the spinal cord. A subset of nociceptors, the nonpepti-dergic C-fibers, is characterized by its reactivity for the plant isolectin B4 (IB4) from Griffonia simplicifolia. The molecular nature of the IB4-reactive glycoconjugate, although used as a neuroanatomical marker for more than a decade, has remained unknown.

13p awards 05-04-2013 35 4   Download

The presenilin proteins are required for intramembrane cleavage of a subset of type 1 membrane proteins including the Alzheimer’s disease amyloid precursor protein. Previous studies indicate presenilin proteins form enzymatically act-ive high molecular mass complexes consisting of hetero-dimers of N- and C-terminal fragments in association with nicastrin, presenilin enhancer-2 and anterior pharynx defective-1 proteins.

11p dell39 03-04-2013 34 4   Download

Bowen’s formula relates the Hausdorff dimension of a conformal repeller to the zero of a ‘pressure’ function. We present an elementary, self-contained proof to show that Bowen’s formula holds for C 1 conformal repellers. We consider time-dependent conformal repellers obtained as invariant subsets for sequences of conformally expanding maps within a suitable class.

55p dontetvui 17-01-2013 55 7   Download

We prove that for any s 0 the majority of C s linear cocycles over any hyperbolic (uniformly or not) ergodic transformation exhibit some nonzero Lyapunov exponent: this is true for an open dense subset of cocycles and, actually, vanishing Lyapunov exponents correspond to codimension-∞. This open dense subset is described in terms of a geometric condition involving the behavior of the cocycle over certain heteroclinic orbits of the transformation.

39p dontetvui 17-01-2013 42 7   Download

We show that every subset of SL2 (Z/pZ) grows rapidly when it acts on itself by the group operation. It follows readily that, for every set of generators A of SL2 (Z/pZ), every element of SL2 (Z/pZ) can be expressed as a product of at most O((log p)c ) elements of A ∪ A−1 , where c and the implied constant are absolute. 1. Introduction 1.1. Background. Let G be a finite group. Let A ⊂ G be a set of generators of G. By definition, every g ∈ G can be expressed as a product of elements of...

24p dontetvui 17-01-2013 44 7   Download

Let f be a real-valued function on a compact set in Rn , and let m be a positive integer. We show how to decide whether f extends to a Cm function on Rn . Introduction Continuing from [F2], we answer the following question (“Whitney’s extension problem”; see [hW2]). Question 1. Let ϕ be a real-valued function defined on a compact subset E of Rn . How can we tell whether there exists F ∈ C m (Rn ) with F = ϕ on E? Here, m ≥ 1 is given, and C m (Rn ) denotes the space...

48p noel_noel 17-01-2013 38 8   Download

We prove that if A is a subset of at least cn1/2 elements of {1, . . . , n}, where c is a sufficiently large constant, then the collection of subset sums of A contains an arithmetic progression of length n. As an application, we confirm a long standing conjecture of Erd˝s and Folkman on complete sequences. o

36p noel_noel 17-01-2013 47 5   Download

A C 1-generic dichotomy for diffeomorphisms: Weak forms of hyperbolicity or infinitely many sinks or sources By C. Bonatti, L. J. D´ ıaz, and E. R. Pujals* A Ricardo Ma˜e (1948–1995), por todo su trabajo n´ Abstract We show that, for every compact n-dimensional manifold, n ≥ 1, there is a residual subset of Diff1 (M ) of diffeomorphisms for which the homoclinic class of any periodic saddle of f verifies one of the following two possibilities: Either it is contained in the closure of an infinite set of sinks or sources (Newhouse phenomenon), or it presents some weak form of...

65p tuanloccuoi 04-01-2013 49 7   Download

We previously reported the construction and activity of a humanized, bispecific diabody (hEx3) that recruited T cells towards an epidermal growth factor receptor (EGFR) positive tumor. Herein, we describe the construction of a second functional, fully humanized, anti-EGFR bispecific diabody that recruits another subset of lymphocyte effectors, the natural killer cells, to EGFR-expressing tumor cells.

11p cosis54 08-12-2012 41 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Recombinant activated protein C: the key is clinical assessment of risk of death, not subset analysis...

2p coxanh_2 24-10-2011 49 5   Download

Adding Restrictions to DataTable and DataColumn Objects As you know, a DataSet object is used to store a copy of a subset of the database. For example, you can store a copy of the rows from database tables into a DataSet

5p daisuphu 29-07-2010 115 6   Download

Accessing a Database Using Visual Studio .NET Visual Studio .NET's Server Explorer allows you to use a subset of the features contained

3p daisuphu 29-07-2010 117 23   Download