The suspect roles

The crystal structure of the complex between human immunodeficiency virus type 1 (HIV-1) protease and a peptidomimetic inhibitor of ethyleneamine type has been refined toRfactor of 0.178 with diffraction limit 2.5 A ˚ .The peptidomimetic inhibitor Boc-Phe-Y[CH2CH2 NH]-Phe-Glu-Phe-NH2 (denoted here as OE) contains the ethylene-amine replacement of the scissilepeptidebond. The inhibitor lacks the hydroxyl group which is believed to mimic tetra-hedral transition state of proteolytic reaction and thus is suspected to be necessary for good properties of peptido-mimetic HIV-1 protease inhibitors.

11p awards 05-04-2013 38 4   Download

The product of gene At3g16450.1 fromArabidopsis thalianais a 32 kDa, 299-residue protein classified as resembling a myrosinase-binding protein (MyroBP). MyroBPs are found in plants as part of a complex with the glucosinolate-degrading enzyme myrosinase, and are suspected to play a role in myrosinase-dependent defense against pathogens.

12p vinaphone15 28-02-2013 30 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: "The role of high-mobility group box-1 (HMGB-1) in the management of suspected acute appendicitis: useful diagnostic biomarker or just another blind alley?

3p toshiba18 31-10-2011 48 3   Download