Tumor marker

Kỹ thuật xác định Tumor maker theo phương pháp này có thể tóm tắt như sau 1. Pha rắn 2. Kháng thể đơn dòng I. 3. Kháng nguyên (Tumor Marker). 4. Kháng thể II và chất phát tin (phóng xạ hay huỳnh quang hoặc enzym). (1) Pha rắn (Steptavidin) - một lớp tráng gắn vào mặt trong thành ống nghiệm. (2) Kháng thể đơn dòng I - gắn vào thành ống nghiệm. (3) Kháng nguyên (Tumor Marker) - có trong huyết tương do tế bào K tiết ra, lúc đó kháng thể I gắn với kháng nguyên tạo phức hợp KN - KT (nhưng chưa...

5p super_doctor 23-10-2010 156 29   Download

EGFR mutation-induced cell proliferation causes changes in tumor biology and tumor metabolism, which may reflect tumor marker concentration and 18F-FDG uptake on PET/CT. Direct aspirates of primary lung tumors contain different concentrations of tumor markers than serum tumor markers, and may correlate better with EGFR mutation than serum tumor markers.

8p vinaypyidaw2711 26-08-2020 9 0   Download

In clinical oncology, only a few applications have been developed using HPV as a personalized tumor marker, a lack most probably related to the limited information obtained by the classical Polymerase Chain Reaction (PCR) approach.

8p viputrajaya2711 22-06-2020 7 0   Download

Carcinoembryonic antigen (CEA) and carbohydrate antigen (CA)19–9 are used in clinical practice as tumor markers to diagnose or monitor colorectal cancer (CRC) patients, However, their specificities and sensitivities are not ideal, and novel alternatives are needed.

9p vibaku2711 22-07-2020 3 0   Download

Gliomas are the most common type of all central nervous system tumors. Almost all patients diagnosed with these tumors have a poor prognostic outcome. We aimed to identify novel glioma prognosis-associated candidate genes.

8p vilisa271 22-09-2020 4 0   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Primary adenocarcinoma of the stomach in von Recklinghausen’s disease with high serum levels of multiple tumor markers: a case report

5p toshiba24 07-12-2011 33 2   Download

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies

7p sting01 15-01-2012 34 2   Download

part 1 book “an atlas of gynecologic oncology” has contents: preoperative workup, cross-sectional and molecular imaging, sigmoidoscopy, cystoscopy, and stenting, radical abdominal hysterectomy, tumor markers, radical vaginal trachelectomy, radical abdominal trachelectomy,… and other contents.

183p tieu_vu13 06-08-2018 24 0   Download

The role of peptidases in carcinogenic processes and their potential usefulness as tumor markers in colorectal cancer (CRC) have been classically attributed to cell-surface enzymes. The objective of the present study was to analyze the activity and mRNA expression of three cytosolic peptidases in the CRC and to correlate the obtained results with classic histopathological parameters for tumor prognosis and survival.

10p viwashington2711 04-12-2019 2 0   Download

We developed a novel plasma amino acid profile-based index (API) to detect ovarian, uterine, cervical, and endometrial cancers. In this study, we aimed to evaluate whether abnormal API values could be normalized after curative treatment in patients with gynecological malignant tumors.

7p vimanila2711 25-06-2020 1 0   Download

Nucleoporin Nup88, a component of nuclear pore complexes, is known to be overexpressed in several types of tumor tissue. The overexpression of Nup88 has been reported to promote the early step of tumorigenesis by inducing multinuclei in both HeLa cells and a mouse model.

12p vibaku2711 22-07-2020 1 0   Download

Circulating cell-free DNA (ccf-DNA) in plasma may contain both specific and non-specific of tumor markers. The concentration and integrity of ccf-DNA may be clinical useful for detecting and predicting cancer progression.

5p vimale2711 25-08-2020 4 0   Download

Glasgow Prognostic Score (GPS) has been reported as a powerful prognostic tool for patients with advanced non–small cell lung cancer (NSCLC). The aim of this study was to assess the relationship between GPS and prognosis related tumor markers in patients with advanced NSCLC.

6p vialabama2711 21-09-2020 6 0   Download

To select optimal candidates for limited lung resection, it is necessary to accurately differentiate the non-invasive tumors from other small-sized lung cancer. Urinary N1 , N12-diacetylspermine (DiAcSpm) has been reported to be a useful tumor marker for various cancers.

8p vialabama2711 21-09-2020 4 0   Download

Upper tract urothelial carcinoma (UTUC) is a tumor with sizable metastases and local recurrence. It has a worse prognosis than bladder cancer. This study was designed to investigate the urinary potential tumor markers of UTUC.

13p virose2711 24-09-2020 3 0   Download

The chemotherapy resistance of non-small cell lung cancer (NSCLC) remains a clinic challenge and is closely associated with several biomarkers including epidermal growth factor receptor (EGFR) ( Drugs 72(Suppl 1):28–36, 012.), p53 ( Med Sci Monit 11(6):HY11–HY20, 2005.) and excision repair cross complementing gene 1 (ERCC1) ( J Thorac Oncol 8(5):582–586, 2013.).

8p vijennie2711 29-09-2020 5 0   Download

Malignant pleural mesothelioma (MPM) is an aggressive malignant tumor of mesothelial origin that shows a limited response to conventional chemotherapy and radiotherapy. Therefore, diagnosing MPM early is very important.

6p vijennie2711 29-09-2020 4 0   Download

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare and heterogeneous neoplasms with overall increasing incidence, but not an associated increase in survival rate over the past few decades. Tumors originate from at least 16 different cells of diffuse endocrine system (DES), scattered through mucosa of gastrointestinal tract. They are mainly sporadic, but sometimes exhibit familial inheritance.

70p wqwqwqwqwq 20-07-2012 40 3   Download

Few studies have simultaneously investigated the role of soluble tumor necrosis factor a (TNFa ) receptors types 1 and 2 (sTNF-R1 and sTNF-R2), C-reactive protein, and interleukin-6 as predictors of cardiovascular events. The value of these inflammatory markers as independent predictors remains controversial.

13p muakhuya 07-07-2012 29 1   Download

Colorectal cancer (CRC) is a major public health issue worldwide, and novel tumor markers may contribute to its efficient management by helping in early detection, prognosis or surveillance of disease. The aim of our study was to identify new serum biomarkers for CRC, and we followed a phased biomarker discovery and validation process to obtain an accurate preliminary assessment of potential clinical utility.

15p cosis54 08-12-2012 31 1   Download