Vaccine and cancer

Cervical cancer is really a public health problem that should be prioritized for prevention, interventions and early screening, especially in developing countries. A cross-sectional study was conducted at a Hanoi Medical University vaccination unit in 2018 to identify the prevalence of and related factors with cervical cancer screening among female clients in Hanoi, Vietnam.

9p vipettigrew 15-03-2023 2 2   Download

Cervical cancer (CxCa) is preventable and treatable via vaccination and screening. Cervicovaginal fluid (CVF) represents the physiological components of the female genital tract. These components are suitable to be utilized for clinical purposes, therefore, making CVF a suitable material for disease screening approaches. Due to high false-negative result rates and low attendance of current expensive routine CxCa screening methods, it has become more important to develop a point-of-care (POC) screening method that every single woman could reach worldwide.

12p lyhuyenthu 31-01-2023 1 1   Download

HPV-related anal cancer occurs in excess rates among people living with HIV (PLWH) and has been increasing in incidence. The HPV vaccine is an effective and safe approach to prevent and reduce the risk of HPVrelated disease. Yet, HPV vaccine programs tailored and implemented in the HIV population are lagging for this highrisk group.

8p viferrari 29-10-2022 2 1   Download

Canine hemangiosarcoma (HSA) is an aggressive cancer arising from multipotential bone marrowderived stem cells. Anthracycline chemotherapy drugs have been the mainstay adjuvant chemotherapy following surgery with only modest improvement in survival and an attendant risk for adverse events.

12p vidarwin 23-02-2022 7 1   Download

Understanding the interactions between tumor and the host immune system is critical to finding prognostic biomarkers, reducing drug resistance, and developing new therapies. Novel computational methods are needed to estimate tumor-infiltrating immune cells and understand tumor–immune interactions in cancers.

16p viaristotle 29-01-2022 9 0   Download

The aim of the study was to investigate the risk of human papillomavirus (HPV) genotyping particularly vaccine genotypes and multiple infections for cervical precancer and cancer, which might contribute to developing genotype-specific screening strategy and assessing potential effects of HPV vaccine.

13p vielonmusk 21-01-2022 11 0   Download

Mutant peptides presented by MHC (major histocompatibility complex) Class II in cancer are important targets for cancer immunotherapy. Both animal studies and clinical trials in cancer patients showed that CD4 T cells specific to tumor-derived mutant peptides are essential for the efficacy of immune checkpoint blockade therapy by PD1 antibody.

9p vitzuyu2711 29-09-2021 6 0   Download

Objectives: Assessment of anti-human colon cancer cell (HT-29 cell) efficacy and activating apoptosis of MeV and MuV combination in vitro. Assessment of C cell tumor efficacy of MeV and MuV combination in nude mice xenograft models.

26p petsematary 02-06-2021 3 0   Download

Neoantigen-based personal vaccines and adoptive T cell immunotherapy have shown high efficacy as a cancer treatment in clinical trials. Algorithms for the accurate prediction of neoantigens have played a pivotal role in such studies.

16p vikentucky2711 24-11-2020 10 0   Download

Human papillomavirus infection is a global social burden that, every year, leads to thousands new diagnosis of cancer. The introduction of a protocol of immunization, with Gardasil and Cervarix vaccines, has radically changed the way this infection easily spreads among people.

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Vaccination against tumor-associated antigens is one promising approach to immunotherapy against malignant gliomas. While previous vaccine efforts have focused exclusively on HLA class I-restricted peptides, class II-restricted peptides are necessary to induce CD4+ helper T cells and sustain effective anti-tumor immunity.

9p vijisoo2711 30-09-2020 5 0   Download

Hormonal treatment might affect the immune response to tumor antigens induced in cancer patients who are being vaccinated. Case presentation: A 33 years-old woman was diagnosed with cutaneous melanoma in May 2009. Her melanoma was located in the intermammary sulcus, had a Breslow thickness of 4 mm, a Clark’s level IV, it was ulcerated and highly melanotic.

5p vijisoo2711 29-09-2020 6 1   Download

The Expanded Program on Immunization currently considers offering Human Papilomavirus vaccine on a routine basis in Vietnam. However, as the current available vaccine can prevent only two types HPV 16 and 18, before implementing a large-scale vaccine campaign we need information about the prevalence of infection with only HPV 16 and 18 in Việt Nam.

7p vijisoo2711 29-09-2020 9 0   Download

Cancer is a significant and growing problem worldwide. While this increase may, in part, be attributed to increasing longevity, improved case notifications and risk-enhancing lifestyle (such as smoking, diet and obesity), hygiene-related factors resulting in immuno-regulatory failure may also play a major role and call for a revision of vaccination strategies to protect against a range of cancers in addition to infections.

10p vijisoo2711 30-09-2020 14 0   Download

HPV is related to a number of cancer types, causing a considerable burden in both genders in Europe. Female vaccination programs can substantially reduce the incidence of HPV-related diseases in women and, to some extent, men through herd immunity.

12p vijisoo2711 30-09-2020 6 0   Download

Data on the current burden of adenocarcinoma (ADC) and histology-specific human papillomavirus (HPV) type distribution are relevant to predict the future impact of prophylactic HPV vaccines. It is predicted that the currently available HPV vaccines will be highly effective in preventing HPVrelated cervical ADC.

12p vijennie2711 29-09-2020 9 0   Download

Cancer vaccine is one of the attractive treatment modalities for patients with castration-resistant prostate cancer (CRPC). However, because of delayed immune responses, its clinical benefits, besides for overall survival (OS), are not well captured by the World Health Organization (WHO) and Response Evaluation Criteria in Solid Tumors (RECIST) criteria.

10p vijennie2711 25-09-2020 10 1   Download

This study aims to assess the most efficient combinations of vaccination and screening coverage for the prevention of cervical cancer (CC) at different levels of expenditure in Nigeria. An optimization procedure, using a linear programming approach and requiring the use of two models (an evaluation and an optimization model), was developed.

16p virose2711 24-09-2020 9 1   Download

Human papillomaviruses (HPV) are the causative agents of cervical cancer in women, which results in over 250 000 deaths per year. Presently there are two prophylactic vaccines on the market, protecting against the two most common high-risk HPV types 16 and 18. These vaccines remain very expensive and are not generally affordable in developing countries where they are needed most.

15p virose2711 24-09-2020 9 0   Download

The vaccinations against human papilloma virus (HPV) are highly effective in preventing persistent infection. The level of knowledge about HPV and the consequences of an infection with this virus are low in the general population and in patients who suffer from HPV-associated diseases.

6p virose2711 24-09-2020 13 1   Download