Value of biomarkers

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis...

    pdf14p thulanh17 27-10-2011 18 4   Download

  • Personalized cancer medicine is defined as medical care based on the particular biological characteristics of the disease process in individual patients. By using genomics and proteomics, individuals can be classified into subpopulations based on their susceptibility to a particular disease or response to a specific treatment. They may then be given preventive or therapeutic interventions that will be most effective given their particular characteristics.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Bench-to-bedside review: The value of cardiac biomarkers in the intensive care patient...

    pdf9p coxanh_4 26-10-2011 20 3   Download

  • Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Clinical values of multiple Epstein-Barr virus (EBV) serological biomarkers detected by xMAP technology

    pdf8p dauphong3 03-01-2012 30 2   Download

  • Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer...

    pdf8p thulanh9 07-10-2011 28 1   Download

  • Lean thinking is not a manufacturing tactic or a cost-reduction program, but a management strategy that is applicable to all organizations because it has to do with improving processes. All organizations — including health care organizations — are composed of a series of processes, or sets of actions intended to create value for those who use or depend on them (customers/patients).

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  • Current investment management practice typically assumes that the OE portfolio is defined by the fund manager’s investment “style.” Roughly, style refers to a subset of the investment universe in which a manager is constrained to operate, such as small capitalization stocks versus large stocks, or “value” versus “growth” firms. The style con- straint may be a self-declared specialization, or it may be imposed on the manager by the firm.

    pdf34p quaivatdo 19-11-2012 27 3   Download

  • EDRN is a leader in defining and using criteria for the validation of biomarkers—an essential condition for scientific progress. While myriad proteins and genes have been linked with a variety of cancers, acceptable biomarkers must be: reliable and repeatable in testing; highly sensitive and specific; quantitative; readily obtained by non-invasive methods; part of the causal pathway for disease; capable of being modulated by the che- mopreventive agent; and have high predictive value for clinical disease.

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  • Alzheimer’s Disease (AD) is an incurable, degenerative, and terminal disease with few therapeutic options [22][23]. It is a complex disease influenced by a range of genetic, environmental, and other factors [23]. Recently, Jack et al.[24] demonstrated the value of shared data in AD biomarker research. A New York Times article on the role of data sharing, in the advancement of AD research, quotes John Trojanowski at the Uni- versity of Pennsylvania Medical School: “It’s not science the way most of us have prac- ticed it in our careers.

    pdf12p thangbienthai 17-11-2012 19 0   Download

  • The objective of this current chapter is to review the techniques whose potential to noninvasively determine Breslow index has been studied. Basic and technical principles of each technique will be mentioned as well as their accuracy in the determination of a factor whose importance in the clinical management of melanoma is so important as previously demonstrated. Currently Breslow index is measured by the anatomo-pathologist after incisional or excisional biopsy of the suspected lesion. So why non invasive determination of Breslow index would be of utmost clinical value?...

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  • The current global epidemic of pulmonary tuberculosis has highlighted the need for new screening tests that are rapid and accurate. The social burden of pulmonary tuberculosis has increased because many patients are also infected with human immunodeficiency virus (HIV), and the rates of multidrug-resistant tuberculosis are increasing.1 However, screening technology has not changed greatly during the past several decades. Many highburden countries depend upon sputum smears and chest radiographs, supplemented by cultures when resources permit.

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  • In practice, signatures that predict toxicity or efficacy can be identified afterwards. For example, therapies targeting the Epidermal Growth Factor Receptor have been first approved before it was demonstrated that mutations in KRAS cancer gene were associated to failures of the relevant therapies in metastatic colorectal carcinoma. This example shows that well-designed retrospective analysis of data from prospective randomized controlled trials can bring forward effective treatments to biomarker defined subgroups of patients in a timely manner.

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  • Recent advances in clinical proteomics have propelled us into an exciting period of discovery of new cancer biomarkers, although the available proteomic technologies have their limitations. The principles of proteomic technology require stringent guidelines for the collection of clinical material, the application of analytical techniques, and for our interpretation of the data. In this review, we present an overview of the serum tumor markers in current use.

    pdf10p connicquy 20-12-2012 40 16   Download


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