Various diseases

To evaluate the treatment results of combined blue light (415 nm wavelength) and red light (633 nm wavelength) therapy for patients with severe acne vulgaris. Subjects and methods: A pre-post comparative interventional study on 30 patients with severe acne vulgaris, examined and treated at the National Hospital of Dermatology and Venereology from July 2022 to June, 2023.

5p vipanly 28-10-2024 2 0   Download

Histomoniasis, commonly known as blackhead disease, is a parasitic disease in poultry caused by the protozoan Histomonas meleagridis. The availability of various compounds for chemotherapy in the 1970s resulted in the successful control of blackhead disease.

13p vibecca 01-10-2024 5 2   Download

Gynostemma pentaphyllum (Thunb.) Makino is a medicinal plant distributed mostly in the mountainous areas of Vietnam. G. pentaphyllum contains more than 189 types of saponin which can be used for the treatment of various diseases.

9p vibecca 01-10-2024 3 2   Download

Hypertrophic cardiomyopathy (HCM) is a common genetic cardiovascular disease and a major cause of sudden death. It is also involved in increasing morbidity and mortality of various cardiovascular diseases. Genetic factors have been found to be important in determining the phenotypic manifestation of cardiac hypertrophy. However, only 50–60% of HCM patients have been identified as having pathogenic variants in known genes, suggesting that more studies are needed to find more disease genes.

15p xuanphongdacy06 18-09-2024 4 1   Download

Obesity is well known that in various human pathological states such as: essential hypertension, coronary heart disease, type 2 diabetes mellitus,... Insulin resistance plays an important role in pathological state of diabetes. Recently, Katz et al provided QUICKI index (Quantitative insulin sensitivity check index) for insulin resistance condition evaluation.

4p vifaye 20-09-2024 4 1   Download

Hepatocellular carcinoma (HCC) is one of the deadliest cancers. Research on HCC so far primarily focused on genes and provided limited information on genomic repeats, which constitute more than half of the human genome and contribute to genomic stability. In line with this, repeat dysregulation was significantly shown to be pathological in various cancers and other diseases. In this study, we aimed to determine the full repeat expression profile of HCC for the first time.

14p thiencuuchu 27-11-2021 21 3   Download

Brucellosis is known as undulant fever or Malta fever, caused by the genus Brucella. It is the most common human zoonosis. The disease is worldwide distributed and causes significant economic losses. In animals, it causes abortion, reduction in milk production, and infertility. While brucellosisin humans is a debilitating disease with various clinical manifestations that may lead to death in some cases.

9p larachdumlanat127 02-01-2021 9 1   Download

Smilax glabra Roxb. is a medicinal plant of Vietnam to treat several diseases such as: Piercing pain in the bones, detoxicating, scabies, nephritis, cystitis, syphilis,... From ethanol extracts of Smilax glabra Roxb. cultivating in Thai Nguyen, 5 compounds were isolated and structurally elucidated in the first time by various spectral methods, such as IR, MS, 1H-NMR, 13C-NMR, DEPT, HSQC, HMBC.

9p larachdumlanat127 20-12-2020 19 3   Download

Rice (Oryza sativa L.) is an important cereal crop and prone to many diseases out ofwhich, rice blast caused by Pyricularia grisea is of significant economic importance due to its destructive nature leading to serious yield loss. Blast infected leaves of rice, Panicum grass and finger millet were collected from different fields of OUAT farm, Bhubaneswar.

6p angicungduoc6 22-07-2020 18 3   Download

Leptospirosis is zoonosis, presenting as a febrile illness with protean manifestations. Since disease is amenable to antibiotic therapy, early diagnosis helps in better management and prevention of complications. In many parts of our country, prevalence is either underestimated or unestimated. Hence this study was conducted with the objective of determining the seroprevalence of leptospirosis among clinically suspected cases, describe the various sociodemographic parameters, occupation and risk factors among seropositive cases.

8p chauchaungayxua6 26-06-2020 63 2   Download

Regulator of G-protein signaling (RGS) proteins were originally identified as negative regulators of G-protein-coupled receptor (GPCR) signaling via their GTPase-accelerating protein (GAP) activity. All RGS proteins contain evolutionarily conserved RGS domain; however, they differ in their size and regulatory domains. RGS1 and RGS10 are smaller than other RGS proteins, and their functions involve various inflammatory responses including autoimmune responses in both the periphery and the central nervous system (CNS). Neuroinflammation is the chronic inflammatory response in the CNS.

5p caothientrangnguyen 09-05-2020 28 2   Download

“Linh chi” - the Vietnamese name for Ganoderma can be used in the prevention and treatment of various types of disease. Various compounds have been isolated from the fruiting bodies, spores, gills, and mycelia of many Ganoderma mushrooms. Ganoderma contains many bioactive natural components, including triterpenes, steroid, polysaccharides, proteins, and unsaturated fatty acids.

7p abcxyz123_02 03-03-2020 11 1   Download

Mitochondrial functional and structural impairment and generation of oxidative stress have been implicated in aging, various diseases and chemotherapies. This study analyzed azidothymidine (AZT)-caused failures in mitochondrial functions, in redox regulation and activation of the HIV-1 gene expression. We monitored intracellular concentrations of ATP and glutathione (GSH) as the indicators of energy production and redox conditions, respectively, during the time-course experiments with U937 and MOLT4 human lymphoid cells in the presence of AZT (0.05 mgÆmL)1) or H2O2 (0.01 mM) for 15–25 days.

7p system191 01-06-2013 42 3   Download

Asheat shockproteins (Hsps) are involved inprotecting cells and also in the pathophysiology of diseases such as inflam-mation, cancer and neurodegenerative disorders, modula-tors ofHsp expression inmammalian cells would seemto be useful for the treatment of various diseases. In this study, we isolated mammalian cell lines for screening of Hsp modu-lators; mouse C3H10T1/2 cells stably transfected with a plasmid containing the mouse Hsp105 or human Hsp70B promoter upstream of a luciferase or b-galactosidase reporter gene, respectively....

8p tumor12 20-04-2013 30 5   Download

The pathogenesis of formation of neurofibrillary tangles (NFTs) in Alzhei-mer’s disease (AD) brains is unknown. One of the possibilities might be that translation of tau mRNA is aberrantly regulated in AD brains.

10p fptmusic 11-04-2013 58 3   Download

X-prolyl dipeptidyl aminopeptidases (X-PDAP) are enzymes catalysing the release of dipeptides from the amino termini of polypeptides containing a proline or an alanine at the penultimate position. Involved in various mam-malian regulation processes, as well as in chronic human diseases, they have been proposed to play a role in pathogenicity forStreptococci.

10p awards 06-04-2013 34 4   Download

Although group IIA secretory phospholipase A2 (sPLA2-IIA) is known to be abundantly present in the joints of patients with rheumatoid arthritis (RA), expression of other sPLA2 s in this disease has remained unknown. In this study, we examined the expression and localization of six sPLA2s (groups IIA, IID, IIE, IIF, V and X) in human RA.

18p awards 05-04-2013 40 4   Download

Homocysteine (Hcy) is anonprotein-forming sulphur amino acid that plays an important role in remethylation and trans-sulphuration processes. In recent years, it has been suggested that increased levels of plasma Hcy may play a role in the pathogenesis of various diseases, particularly at the cardiovascular level. The pathogenic mechanism of hyperhomocysteinemia, however, has not been clarified.

6p dell39 03-04-2013 54 3   Download

Considerable attention has been paid to the high cytotoxic potential of small, prefibrillar aggregates of proteins⁄peptides, either associated or not associated with amyloid diseases. Recently, we reported that different cell types are variously affected by early aggregates of the N-terminal domain of the prokaryotic hydrogenase maturation factor HypF (HypF-N), a pro-tein not involved in any disease.

17p inspiron33 26-03-2013 39 4   Download

Recently, we reported that the transient expression of huntingtin exon1 polypeptide containing polyglutamine tracts of various sizes (httEx1-polyQ) in cell models of Huntington disease generated an oxidative stress whose intensity was CAG repeat expansion-dependent.

14p inspiron33 23-03-2013 31 2   Download